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Candidate found to inhibit malignant melanoma growth: Possible early warning sign for skin cancer sciencedaily.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from sciencedaily.com Daily Mail and Mail on Sunday newspapers.
Candidate found to inhibit malignant melanoma growth asiaresearchnews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from asiaresearchnews.com Daily Mail and Mail on Sunday newspapers.
Malignant melanoma is a relatively aggressive type of skin cancer. When detected early, it is usually treatable by surgical resection only, but metastases develop often spreading to distant areas. ....
Cancer-associated fibroblasts (CAFs) are key factors in the tumor microenvironment, which have been implicated in cancer cell progression. It has also been reported that vesicles called exosomes produced by these CAFs play an important role in cancer progression. An Osaka Metropolitan University research group investigated the effect of CAF-derived exosomes on the growth of malignant melanoma cells. They found that CAF-derived exosomes express CD9 and CD63 transmembrane proteins, and that the CD9-positive exosomes may inhibit the growth of malignant melanoma cells. ....