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News Scan for Apr 22, 2021

No safety signals found in pregnant women who received mRNA vaccines
Preliminary findings from a large analysis of pregnant women who received mRNA COVID-19 vaccines showed no obvious safety signals, Centers for Disease Control and Prevention (CDC) researchers reported yesterday in the
New England Journal of Medicine.
Using data voluntarily reported to three US vaccine safety monitoring systems the v-safe after vaccination health checker surveillance system, the v-safe pregnancy registry, and the Vaccine Adverse Event Reporting System (VAERS) the researchers examined outcomes among 35,691 pregnant women who received either the Pfizer/BioNTech or Moderna vaccines from Dec 14, 2020 through Feb 28. Outcomes included local and systemic reactogenicity, participant-reported pregnancy outcomes, neonatal outcomes, and pregnancy- and neonatal-specific adverse events. ....

Romania General , N Englj Medstudy , Centers For Disease , World Organization For Animal Health , Disease Control , New England Journal , Vaccine Adverse Event Reporting System , Public Health , World Organization , Animal Health , ரோமானியா ஜநரல் , மையங்கள் க்கு நோய் , உலகம் ஆர்கநைஸேஶந் க்கு விலங்கு ஆரோக்கியம் , நோய் கட்டுப்பாடு , புதியது இங்கிலாந்து இதழ் , பொது ஆரோக்கியம் , உலகம் ஆர்கநைஸேஶந் , விலங்கு ஆரோக்கியம் ,

COVID-19 Scan for Apr 16, 2021

Scientists tie platelet factor 4 to AstraZeneca COVID vaccine-related clots
UK researchers have uncovered the novel mechanism behind rare abnormal blood clotting seen in some AstraZeneca/Oxford vaccine recipients, according to a study today in the
New England Journal of Medicine.
The study involved clinical and lab evaluation of 23 previously healthy patients who experienced blood clots and thrombocytopenia (low platelet counts) 6 to 24 days after receiving the first dose of the AstraZeneca vaccine. Most clots were cerebral venous thrombosis, while some were arterial thrombosis and venous thromboembolisms such as pulmonary embolisms.
Twenty-one patients had antibodies for clot-promoting platelet factor 4 (PF4) on enzyme-linked immunosorbent assay (ELISA) before heparin administration. They appeared to be of the immunoglobulin G (IgG) subtype. Functional heparin-induced thrombocytopenia (HIT) testing confirmed the positive PF4 ELISA result in five of seven patients ....

United Kingdom , Astrazeneca Oxford , Carlos Guijarro , Stuart Sealfon , Universitario Fundacion Alcorcon , N Englj Medstudy , Maria Velasco , Naval Medical Research Center , Icahn School Of Medicine At Mount Sinai , New England Journal , Lancet Respiratory , Icahn School , Mount Sinai , Hospital Universitario Fundacion Alcorcon , ஒன்றுபட்டது கிஂக்டம் , மரியா வெலாஸ்கோ , கடற்படை மருத்துவ ஆராய்ச்சி மையம் , இக்ஹ்ன் பள்ளி ஆஃப் மருந்து இல் ஏற்ற சினை , புதியது இங்கிலாந்து இதழ் , இக்ஹ்ன் பள்ளி , ஏற்ற சினை ,

COVID-19 Scan for Jan 14, 2021

Phase 1 and 2 trials show J&J COVID vaccine safe, immune-producing
Interim phase 1-2a results from Johnson & Johnson s COVID-19 vaccine trials show that its vaccine, Ad26.COV2.S, produces a good immune response and safety profile, according to a
New England Journal of Medicine study yesterday.
Unlike the two messenger-RNA vaccines currently in use in the United States, the Johnson & Johnson vaccine uses a recombinant, non-replicating adenovirus 26 (Ad26) with a complete and stabilized spike protein.
A single dose of Ad26.COV2.S elicited a strong humoral response in a majority of vaccine recipients, with the presence of S-binding and neutralizing antibodies in more than 90% of participants, regardless of either age group or vaccine dose, write the researchers. ....

New York , United States , N Englj Medstudy , Houston Methodist Research Institute , Human Services , Drug Administration , New York Times , Clemson University , Us Department Of Health , New England Journal , Charlson Comorbidity Index , Hispanic Asian , புதியது யார்க் , ஒன்றுபட்டது மாநிலங்களில் , ஹூஸ்டன் முறை ஆராய்ச்சி நிறுவனம் , மனிதன் சேவைகள் , புதியது யார்க் முறை , கிளெம்சன் பல்கலைக்கழகம் , எங்களுக்கு துறை ஆஃப் ஆரோக்கியம் , புதியது இங்கிலாந்து இதழ் , ஹிஸ்பானிக் ஆசிய ,