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IVIG a Winner for Dermatomyositis


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Treatment with intravenous immunoglobulins (IVIG) for dermatomyositis was effective in a pivotal phase III randomized trial, a researcher reported.
At week 16, 78.72% of patients receiving IVIG were considered responders versus 43.75% among those given placebo, which represented a difference of 34.97% (95% CI 16.70-53.24,
P=0.0008). This was a highly significant difference, said Rohit Aggarwal, MD, co-director of the Myositis Center at the University of Pittsburgh, during a plenary abstract session at the European League Against Rheumatism (EULAR) virtual congress.
Dermatomyositis is a rare, chronic autoimmune disease characterized by progressive proximal muscle weakness and a characteristic skin rash, he explained. Current therapeutic options include corticosteroids, other immunosuppressants, and IVIG. However, none of these therapies have been evaluated in phase III studies. ....

Dermatomyositis Pro , Nancy Walsh , Rohit Aggarwal , Myositis Center , University Of Pittsburgh , American College Of Rheumatology , Regina College In Newport , Peuropean League Against Rheumatism , United Statesa , Salve Regina College , League Against , Skin Rash , Venous Thrombosis , Deep Venous Thrombosis , நான்சி வால்ஷ் , பல்கலைக்கழகம் ஆஃப் பிட்ஸ்பர்க் , அமெரிக்கன் கல்லூரி ஆஃப் வாத நோய் , ரெஜினா கல்லூரி இல் நியூபோர்ட் , ஐரோப்பிய லீக் எதிராக வாத நோய் , சால்வ் ரெஜினா கல்லூரி , லீக் எதிராக , தோல் ரஷ் , சிரை த்ரோம்போசிஸ் , ஆழமான சிரை த்ரோம்போசிஸ் ,