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Updated MANIFEST-2 Data With Pelabresib/Ruxolitinib Support Paradigm Shift in Myelofibrosis

Updated MANIFEST-2 Data With Pelabresib/Ruxolitinib Support Paradigm Shift in Myelofibrosis
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Memorial sloan kettering cancer centerNew yorkUnited statesRaajitk rampalDynamic international prognostic scoring systemDepartment of medicineLeukemia serviceTrial designBaseline diseaseMyelofibrosis symptom assessment form

GSK : New data at ASCO showcases the transformational potential of GSK s oncology portfolio

DREAMM-8 results for Blenrep in multiple myeloma featured in a late-breaking presentation and ASCO s Press Programme Updated results from a supported.

United kingdomUnited statesHong kongHansoh pharmaBelantamab mafodotinDrug administrationAmerican society of clinical oncologyBiowa incKyowa kirin groupAnaptysbio incEuropean commissionMemorial sloan kettering cancer centerRegulatory agencyJapanese society of medical oncology annual meetingsSeagen incIvy brain tumor center

Parsaclisib Added to Ruxolitinib Decreases Spleen Volume and Improves Symptom Scores in Myelofibrosis

Add-on parsaclisib with ruxolitinib resulted in decreased spleen volume and improved symptom assessment scores in patients with myelofibrosis.

Kansas cityUnited statesAbdulraheem yacoubKu medical centerMyelofibrosis symptom assessment formHematologic malignanciesCellular therapeuticsPatient global impressionParsaclisib with ruxolitinibPatients with myelofibrosis

Investigators Set to Explore Selinexor Monotherapy or Plus Ruxolitinib in JAK Inhibitor–Naive Myelofibrosis

Selinexor is under investigation as monotherapy and in combination with the JAK inhibitor ruxolitinib in patients with JAK inhibitor–naive myelofibrosis.

Johno mascarenhasDynamic international prognostic scoring systemAdult leukemia programTisch cancer instituteMyeloproliferative disorders programIcahn school of medicine at mount sinaiIcahn schoolMount sinaiBlood cancersMyeloid disordersMyeloproliferative disordersMyelofibrosis symptom assessment formAdv hematolJak inhibitor naive myelofibrosisXport mf 044Xport mf 034

Momelotinib Approved in Europe for Myelofibrosis With Anemia

Momelotinib gets market authorization from the European Commission for patients with MPNs and disease-related splenomegaly or moderate to severe anemia.

Nina mojasEuropean commissionEuropean unionOncology global product strategyMyelofibrosis symptom assessment formTotal symptom scoreHase 3 momentum trial nct04173494Phase 3 simplify 1 trial nct01969838