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Designer DNA drug could be used to delay paralysis in ALS

In virtually all persons with amyotrophic lateral sclerosis (ALS) and in up to half of all cases of Alzheimer's disease (AD) and frontotemporal dementia, a protein called TDP-43 is lost from its normal location in the nucleus of the cell. ....

Don Cleveland , Emily Henderson , Cancer Research , Cancer Research Industry , Distinguished Professor , Molecular Medicine , California San Diego School , Research Industry Focus , Lzheimer 39s Disease , Amyotrophic Lateral Sclerosis , Frontotemporal Dementia , Motor Neurons , Nervous System , Neurodegenerative Diseases , Tdp 43 ,

Innate immune molecule could be at the root of ALS

While drugs are on the market to slow the progression of neurodegenerative diseases, there are still no cures. ....

United States , Harvard University , Himanish Basu , Dylan Neel , Isaac Chiu , Emily Henderson , Judy Lieberman , Harvard Medical School , Boston Children , Industry Focus , Amyotrophic Lateral Sclerosis , Immune System , Medical School , Motor Neuron Disease , Motor Neurons , Neurodegenerative Diseases ,

USC researchers identify two promising avenues for developing new ALS treatments

Each year in the U.S., 5,000 patients receive a diagnosis of ALS, an incurable neurodegenerative disease that will likely kill them within two to five years. ....

New York , United States , Samuelv Alworth , Wen Hsuan Chang , Stacee Mendonca , Justin Ichida , Emily Henderson , Lou Gehrig , Jonathan Chang , Yichen Li , Gabriel Linares , Emanuel Santana , Sarah Hong , Yunsun Eoh , Joscany Perez , Broad Institute Of Harvard , York Stem Cell Foundation , Acurastem Inc , Ichida Lab , Cell Stem , Connectivity Map , Broad Institute , Genomics Industry Focus , John Douglas French Alzheimer , Foundation Associate Professor , Stem Cell Biology ,

Study offers clues about the biology of cells in the spinal cord that die off in ALS

New research offers clues about the biology of cells in the spinal cord that die off in amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases. ....

Emily Henderson , National Institutes Of Health , National Institutes , Motor Neurons , Amyotrophic Lateral Sclerosis , Medical Research , Nervous System , Neurodegenerative Diseases ,

Lab grown mature neurons hold promise for neurodegenerative disease therapy

Researchers have created the first mature neurons from human induced pluripotent stem cells, offering potential for new neurodegenerative disease therapies. ....

Elissa Wolfson , Samueli Stupp , Science Advisory Board , Cell Stem , Human Induced Pluripotent Stem Cells , Pscs Patient Specific Ipscs , Motor Neurons , Cortical Neurons , Eurodegenerative Disease , Eurodegenerative Disease Therapy , Stem Cell Transplantation , Ynthetic Nanofiber Coatings , Amyotrophic Lateral Sclerosis , Arkinson 39s Disease , Lzheimer 39s Disease , Multiple Sclerosis , Ifferentiated Stem Cells , Spinal Cord Injuries , Ging Related Illnesses , Adult Onset Diseases , Northwestern University ,