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Research provides first evidence for a possible cause of familial ALS

Amyotrophic lateral sclerosis (ALS) is a degenerative disease. The neurons responsible for movement begin to die and muscle control is progressively lost, leading to a fatal outcome. ....

Oleksandra Sirozh , Vanesa Lafarga , Fernandez Capetillo , Francisco Luz , Ministry Of Science , Genomic Instability Group , Spanish National Cancer Research Center , Caixa Foundation , Spanish Association Against Cancer , European Union , Nacional De Investigaciones Oncol , Molecular Cell , Amyotrophic Lateral Sclerosis , Degenerative Disease , Motor Neurons ,

Study proposes novel approach to slow neuromuscular degeneration in ALS patients

A study led by the Center for Biomaterials and Tissue Engineering of the Universitat Politècnica de València, member of Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine, in collaboration with the Instituto de Investigación Sanitaria La Fe and the University of Zaragoza proposes a novel approach to slow neuromuscular degeneration in patients with Amyotrophic Lateral Sclerosis. ....

Fran Ferrer , Juan Francisco , Eduardo Rubio , Sant Crist , Research Group In Neuromuscular Pathology , Biomedical Research Networking Center , Stopela Association , University Of Zaragoza Unizar , Stopela Patient Association , Tissue Engineering , Universitat Polit , Instituto De Investigaci , Amyotrophic Lateral Sclerosis , Patricia Rico , Motor Neuron Diseases Unit , Hospital Universitari , Research Group , Neuromuscular Pathology , Amyotrophic Lateral Sclerosis , Motor Neurons , Ouse Model , Neurodegenerative Diseases , Tissue Engineering ,

New drug targets key mechanism in ALS, protects motor neurons

A new pharmacological inhibitor can intervene in a central cell death mechanism that is responsible for the death of motor neurons and hence important for the progression of the motor neuron disease amyotrophic lateral sclerosis (ALS). ....

Baden Wüberg , Hilmar Bading , Jing Yan , Department Of Neurobiology , Interdisciplinary Center , European Research Council , Heidelberg University , German Research Foundation , Alexander Von Humboldt Foundation , Fundamental Pharma , Amyotrophic Lateral Sclerosis , Ell Death , Degenerative Disease , Motor Neuron Disease , Motor Neurons , Ouse Model , Nervous System ,

ALS progression linked to mitochondria-associated membrane-ER disconnection

Researchers at Nagoya University in Japan have discovered a relationship between the progression of amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, and the disruption of mitochondria-associated membranes (MAM), the contact point between the mitochondria and the endoplasmic reticulum (ER) of the cell. ....

Lou Gehrig , Seiji Watanabe , Masahisa Katsuno , School Of Medicine , Proceedings Of The National Academy Sciences , Researchers At Nagoya University , Nagoya University , National Academy , Koji Yamanaka , Research Institute , Environmental Medicine , Graduate School , Amyotrophic Lateral Sclerosis , Lou Gehrig 39s Disease , Motor Neurons ,

Webinar: Empowering motor neuron disease research and drug discovery with a new class of functional, reproducible hiPSC-derived motor neurons

Webinar: Empowering motor neuron disease research and drug discovery with a new class of functional, reproducible hiPSC-derived motor neurons
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