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Transcripts for BBCNEWS BBC News 20210811 12:51:00

It s a game changer. it is absolutely changed the face of sma. this is when he was seven weeks old in hospital. he had just been resuscitated by his dad. later diagnosed with severe spinal muscular atrophy. the vectors deliver new working copies of sma genes to the motor neuron cells. this new, one off drug contains a replica of the missing gene, halting the progression of the disease, helping babies breathe without a ventilator and even crawl and walk. he shouldn t really feel anything. he s got a cannula in, which is a little bit of plastic into his vein. and the drug just goes through that over an hour. injune, five month old arthur became the first baby to receive this revolutionary treatment on the nhs. now edward is one of a handful of babies being treated for the first time at the children s ....

Game Changer , Sheffield Childrens Hospital , Motor Neuron Cells , Sma Genes , Cannula In , He Shouldn T , Childrens Hospital ,

Transcripts for BBCNEWS BBC News 20210811 13:49:00

Administered at the children s hospital in sheffield. without medical intervention, he wouldn t live to his second birthday. his parents have been scared he wouldn t get this amazing chance of life. yay! we re just so relieved, excited, scared, apprehensive, nervous absolutely, completely petrified. it s a game changer. it has absolutely changed the face of sma. this is when he was seven weeks old in hospital. he had just been resuscitated by his dad. later diagnosed with severe spinal muscular atrophy. the vectors deliver new working copies of sma genes to the motor neuron cells. this new, one off drug contains a replica of the missing gene, halting the progression of the disease, helping babies breathe without a ventilator and even crawl and walk. he shouldn t really feel anything. he s got a cannula in, which is a little bit of plastic into his vein. and the drug just goes ....

Sheffield Childrens Hospital , Childrens Hospital , Wouldn T , Game Changer , Spinal Muscular Atrophy , Motor Neuron Cells , Sma Genes , Cannula In , He Shouldn T ,

Transcripts for BBCNEWS BBC News 20210811 14:26:00

£1.79 million and is administered at the children s hospital in sheffield. without medical intervention, he would not live until his second birthday point of his parents have been scared he would not get the amazing chance of life. we would not get the amazing chance of life. ~ ., , would not get the amazing chance of life. 2 . , ,., ., life. we are ust so relieved and excited, life. we are just so relieved and excited, scared life. we are just so relieved and excited, scared and life. we are just so relieved and i excited, scared and apprehensive. nervous. absolutely completely petrified! it is a game changer, it is absolutely changed the face of sma. , ., , ., , , sma. this was when he was seven weeks old in sma. this was when he was seven weeks old in hospital sma. this was when he was seven weeks old in hospital having i sma. this was when he was seven weeks old in hospital having just l weeks old in hospital having just been resuscitated by his dad put it was later diagno ....

Sheffield Childrens Hospital , Childrens Hospital , 6 79 Million , 1 79 Million , Game Changer , Life 2 , Spinal Muscular Atrophy , Motor Neuron Cells , Working Copies , Shouldn T , Cannula In , He Shouldn T , Gota Cannula In , Helping Babies Breed ,

Transcripts for BBCNEWS The Papers 20240604 21:36:00

In the world, obviously. what s incredible is that this treatment may permanently stop any further treatment may permanently stop any furthe . ,. . ., it contains a healthy copy of a missing or faulty gene called smn1. this is inserted into a harmless virus. in the body, the virus delivers the replacement gene into the nucleus of motor neuron cells. this is essential to prevent those cells from gradually dying. the now healthy motor neuron cells start producing the missing smn1 protein. this has opened up a door for other genetic diseases, cystic fibrosis, and all types of other rare diseases. matthew hill, bbc points west. some other infants have seen their condition notjust stabilise, but in proof, and week later, riley s mum is very optimistic. ....

Replacement Gene , Motor Neuron , Motor Neuron Cells , Cystic Fibrosis , Smn1 Protein , Riley Cadle Birch , Bbc News , Matthew Hill , Points West , Condition Notjust Stabilise ,

Transcripts for BBCNEWS BBC News 20240604 20:50:00

Quality of life there, so we managed to do that. he is been improving with his movement and his breathing, so they decided to have a big meeting about it and he got approved for it, which was the best feeling in the world, obviously. so how does the drug were? so how does the drug work? it contains a healthy copy of a missing or faulty gene called smn1. this is inserted into a harmless virus. in the body, the virus delivers the replacement gene into the nucleus of motor neuron cells. this is essential to prevent those cells from gradually dying. the now healthy motor neuron cells start producing the missing smn1 protein. this has opened up a door for other genetic diseases, cystic fibrosis, and all types of other rare diseases. matthew hale, bbc points west. matthew hill, bbc points west. the world health organisation has urged extreme caution ....

Replacement Gene , Smn1 Protein , Motor Neuron Cells , Cystic Fibrosis , Motor Neuron , Bbc News , Points West , Matthew Hill , World Health Organisation , Matthew Hale ,