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By Sarah Constantin (blog - 1, 2) The More Dakka story is common in medicine. You do an intervention; the disease doesn't get better, or gets only marginally better; the research literature concludes it doesn't work; nobody tries doing MORE of that intervention, but when somebody just raises the dose high enough, it does work. Examples:… ....
LESSWRONG Today, the FDA is meeting to discuss Pfizer’s Covid-19 vaccine. By the time many of you read this, they will have hopefully given the vaccine, and perhaps Moderna’s as well, emergency use authorization. If that happens, distributions to the states can begin, and some people will be vaccinated as early as tomorrow. That is excellent news. Alas, supplies remain highly limited and the vaccine takes a month to work. States are getting smaller allocations of the vaccine than they expected. The situation for the holiday season remains unchanged, and most of us will likely not become immune until some time around May. ....