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What is the role of macrophage origin, function, and heterogeneity in health and disease?

In a new study, researchers examined the wealth of information available regarding the heterogeneity of tissue macrophages. ....

Aimee Molineux , Neha Mathurnov , Neha Mathur , Triggering Receptor Expressed On Myeloid Cells , Bone Marrow ,

SARS-CoV-2 activates NLRP3 inflammasome

Researchers assessed the role of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the NLR family pyrin domain containing 3 (NLRP3) inflammasome activation. ....

Juan Gaertner Shutterstock , Lab Diagnostics Automation , Lab Diagnostics Automation Industry , Molecular Psychiatry , Automation Industry Focus , Coronavirus Disease Covid 19 , Ars Cov 2 , Ngiotensin Converting Enzyme 2 , Covid 19 , Arkinson 39s Disease , Evere Acute Respiratory , Evere Acute Respiratory Syndrome , Spike Protein ,

The epigenetic alterations of monocytes in severe COVID-19

Researchers performed DNA methylation analysis on monocytes in the peripheral blood samples obtained from severe COVID-19 patients. ....

Comunidad Autonoma De Cataluna , Hebron University Hospital , Infinium Methylation , Sequential Organ Failure Assessment , Coronavirus Disease Covid 19 , Covid 19 , Acute Respiratory Distress Syndrome , Na Methylation , Immune Response , Ars Cov 2 , Evere Acute Respiratory , Evere Acute Respiratory Syndrome ,

The immunometabolic regulatory mechanisms for the pathogenesis of COVID-19

A new study aimed to analyze the immunometalobism BALF cells from mild to severe COVID-19 patients using computational algorithms that quantified metabolic fluxes and metabolic pathways. ....

World Health Organization , Coronavirus Disease Covid 19 , Covid 19 , Ene Expression , Immune Response , Ars Cov 2 , Evere Acute Respiratory , Evere Acute Respiratory Syndrome , Ignaling Pathway ,

What is the association between interferon genes and complement regulatory protein expressions in SARS-CoV-2 infections?

Researchers investigated the expression of complement regulatory proteins (CRPs) in coronavirus disease 2019 (COVID-19) to identify potential dysregulated CRP patterns and investigate whether they contribute to COVID-19 pathogenesis. ....

Mongkolchon Akesin Shutterstock , Image Credit , Coronavirus Disease Covid 19 , Ars Cov 2 , Covid 19 , Ibonucleic Acid , Evere Acute Respiratory , Evere Acute Respiratory Syndrome , T Lymphocyte ,