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Giraffe genome holds keys to its peculiar body—and clues to hypertension treatments


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Researchers are uncovering the mutations that give giraffes like this pair from Uganda their unique physique.
JAN VERMEER/MINDEN PICTURES
Giraffe genome holds keys to its peculiar body and clues to hypertension treatments
Mar. 17, 2021 , 2:00 PM
To biologists, the giraffe’s long neck is a prime example of evolution’s handiwork, cited by both Charles Darwin and Jean-Baptiste Lamarck as support for their evolutionary theories. But it is also an engineering problem. In order to get oxygen up its 2-meter neck to its brain, a giraffe’s heart constantly pumps blood at a pressure roughly 2.5 times higher than is normal in humans. Now, a new giraffe genome is revealing genetic alterations that allow these animals to live happily with hypertension along with other genes linked to giraffes’ unusual physique. ....

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