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"Incorporating clinical imaging into the delivery of microbeam radiatio" by Jason Paino, Micah Barnes et al.

Synchrotron microbeam radiation therapy is a promising pre-clinical radiation treatment modality; however, it comes with many technical challenges. This study describes the image guidance protocol used for Australia’s first long-term pre-clinical MRT treatment of rats bearing 9L gliosarcoma tumours. The protocol utilises existing infrastructure available at the Australian Synchrotron and the adjoining Monash Biomedical Imaging facility. The protocol is designed and optimised to treat small animals utilising high-resolution clinical CT for patient specific tumour identification, coupled with conventional radiography, using the recently developed SYNCMRT program for image guidance. Dosimetry performed in small animal phantoms shows patient dose is comparable to standard clinical doses, with a CT associated dose of less than 1.39 cGy and a planar radiograh dose of less than 0.03 cGy. Experimental validation of alignment accuracy with radiographic film demonstrates end to end accuracy of ....

South Australia , Australian Synchrotron , Monash Biomedical Imaging , Image Guidance , N Vivo , Microbeam Radiation Therapy ,

Lower risk of brain injury for at-risk infants whose mothers consumed pomegranate juice


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Intrauterine growth restriction (IUGR) is common and concerning, but few therapeutic options exist for pregnant mothers who receive this diagnosis. IUGR is a condition in which a baby in the womb is measuring small for its gestational age, often because of issues with the placenta, resulting in compromised or insufficient transfer of oxygen and nutrients to the growing fetus. The developing fetal brain is particularly vulnerable to these effects. One out of every 10 babies is diagnosed with IUGR, and infants with IUGR are at increased risk of death and neurodevelopmental impairment. Recent research on polyphenol-rich pomegranate juice has suggested that it may help protect the brain from injury. In an exploratory, randomized, controlled clinical trial, supported by philanthropic funding and a gift from POM Wonderful, the largest grower and producer of fresh pomegranates and pomegranate juice in the United States, investigators at Brigham and Women s Hospital enrolled ....

South Australia , United States , Lilliang Matthews , Terrie Inder , Los Angeles , Department Of Pediatric , Women Hospital Program For Interdisciplinary Neuroscience Award , Turner Institute For Brain , Mental Health , Harvard Medical School , Department Of Pediatric Newborn Medicine , Pediatric Newborn Medicine , Monash Biomedical Imaging , Turner Institute , Newborn Medicine , Hospital Program , Interdisciplinary Neuroscience Award , Medicine Health , Developmental Reproductive Biology , Parenting Child Care Family , தெற்கு ஆஸ்திரேலியா , ஒன்றுபட்டது மாநிலங்களில் , டெர்ரி இண்டேர் , லாஸ் ஏஞ்சல்ஸ் , துறை ஆஃப் குழந்தை , பெண்கள் மருத்துவமனை ப்ரோக்ர்யாம் க்கு இடைநிலை நரம்பியல் விருது ,