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Brain's waste removal system may offer path to better outcomes in Alzheimer's therapy | National Institutes of Health (NIH)


NIH-funded study in mice suggests lymphatic boost could help reduce amyloid buildup.
Study of mouse brain shows the meningeal lymphatics system (purple and pink) could help reduce amyloid. Sandro Da Mesquita, Ph.D.
Enhancing the brain’s lymphatic system when administering immunotherapies may lead to better clinical outcomes for Alzheimer’s disease patients, according to a new study in mice. Results published April 28 in
Nature suggest that treatments such as the immunotherapies BAN2401 or aducanumab might be more effective when the brain’s lymphatic system can better drain the amyloid-beta protein that accumulates in the brains of those living with Alzheimer’s. Major funding for the research was provided by the National Institute on Aging (NIA), part of the National Institutes of Health, and all study data is now freely available to the broader scientific community. ....

Jonathan Kipnis , Richardj Hodes , Mollyv Wagster , Behavioral Systems Neuroscience Branch , Us Department Of Health , Human Services , National Institutes Of Health , Discovery Into Health , Washington University School Of Medicine , Division Of Neuroscience , Research Implementation Milestone , National Institute On Aging , National Institute , National Institutes , Systems Neuroscience Branch , Washington University School , Implementation Milestone , Dementias Education , Turning Discovery Into , Lymphatic System , Alzheimers Disease , ஜொனாதன் கிப்னிச் , எங்களுக்கு துறை ஆஃப் ஆரோக்கியம் , மனிதன் சேவைகள் , தேசிய நிறுவனங்கள் ஆஃப் ஆரோக்கியம் , கண்டுபிடிப்பு க்குள் ஆரோக்கியம் ,

Brain's waste removal system may offer path to better outcomes in Alzheimer's therapy


HIN
Enhancing the brain’s lymphatic system when administering immunotherapies may lead to better clinical outcomes for Alzheimer’s disease patients, according to a new study in mice. Results published April 28 in Nature suggest that treatments such as the immunotherapies BAN2401 or aducanumab might be more effective when the brain’s lymphatic system can better drain the amyloid-beta protein that accumulates in the brains of those living with Alzheimer’s. Major funding for the research was provided by the National Institute on Aging (NIA), part of the National Institutes of Health, and all study data is now freely available to the broader scientific community. ....

Jonathan Kipnis , Richardj Hodes , Mollyv Wagster , Division Of Neuroscience , Behavioral Systems Neuroscience Branch , Research Implementation Milestone , National Institutes Of Health , Washington University School Of Medicine , National Institute On Aging , National Institute , National Institutes , Systems Neuroscience Branch , Washington University School , Implementation Milestone , Dementias Education , ஜொனாதன் கிப்னிச் , பிரிவு ஆஃப் நரம்பியல் , தேசிய நிறுவனங்கள் ஆஃப் ஆரோக்கியம் , வாஷிங்டன் பல்கலைக்கழகம் பள்ளி ஆஃப் மருந்து , தேசிய நிறுவனம் , தேசிய நிறுவனங்கள் , வாஷிங்டன் பல்கலைக்கழகம் பள்ளி ,