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New study reveals mast cells' surprising role in allergy-related avoidance behavior

Researchers showed that mast cells and IgE are the key orchestrators of antigen-specific avoidance.

Katerynakon-shutterstock
Margie-profet
Allergy
Antibodies
Ntigen
Fell
Diarrhea
Immune-response
Immune-system
Immunity
Mmunoglobulin

IgA nephropathy: The disease that lies outside the kidney

The cause of a common kidney disease likely lies outside the kidney, according to a new study led by Columbia University researchers.

Ali-gharavi
Jay-meltzer
Lily-ramsey
Krzysztof-kiryluk
Columbia-university
Columbia-university-vagelos-college-of-physicians
Columbia-university-vagelos-college
Kidney
Kidney-disease
Na
Drugs
Genes

Study suggests the role of histamine-releasing factor in severe asthma and RV-induced asthma exacerbation

Asthma is more dangerous than many people realize. An estimated 10 Americans die everyday from asthma, and the disease leads to around 439,000 hospitalizations and 1.3 million emergency room trips each year.

United-states
Boston
Massachusetts
Americans
Toshiaki-kawakami
Danielle-ellis
University-of-virginia
University-of-pittsburgh-school-medicine
Kawakami-lab
Jolla-institute-for-immunology
Professor-toshiaki-kawakami
Clinical-immunology

Patients with high-risk chronic lymphocytic leukemia may benefit from treatment with ibrutinib plus venetoclax

First-line ibrutinib (Imbruvica) plus venetoclax (Venclexta) led to high response and survival rates in patients with chronic lymphocytic leukemia (CLL) whether or not their cancer harbored high-risk genetic features typically associated with poor outcomes, according to results published in Clinical Cancer Research, a journal of the American Association for Cancer Research (AACR).

United-states
American
Megan-craig
John-allan
Genentech
American-association-for-cancer-research
Clinical-cancer-research
Astrazeneca
American-association
Cancer-research
Weill-cornell
Adaptive-biotechnologies

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