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The UK has a strong genetics research base: but to date, academics have found it difficult to progress gene therapy research into clinical trials and beyond. The Sheffield Gene Therapy Innovation and Manufacturing Centre (GTIMC) is one of three new hubs, announced this month, that will tackle these challenges.
The investment in the three ‘cutting-edge hubs’ totals £18m ($24.9m), with the sites dedicated to advancing the clinical development of new genetic treatments.
The Sheffield hub will also include a GMP (good manufacturing practice) facility that will support gene therapy projects emerging from universities across the UK. As well as manufacturing clinical grade adeno-associated viruses (AVV), it will also be ready to investigate ways to ‘radically increase yields and reduce productivity barriers in future years’.    ....

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