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Detecting the presence of the virus requires amplifying the numbers of the biomarker, such as the copies of viral ribonucleic acid (RNA) in the common polymerase chain reaction technique for Covid-19 detection, or amplifying the binding signal for a target biomarker.The ....
Abstract Fluid movement is critical in textile-based microfluidic devices with post-processing approaches commonly used to enhance the wicking rate of textile-based microfluidic devices. In this work, for the first time, we have demonstrated composite fibre approach as an effective, easy, tunable and cost-effective technique with long-lasting effect to change the fibres surface chemistry. This approach incorporates commercially sourced polyester yarns and a low-density polyethylene (LDPE) - liquid crystalline graphene oxide (LCGO) composite fibre integrated into a circular knitted structure. Our technique improves the mechanical properties of the resultant fibres and provides a facile route for tuning the wicking properties of textile-based microfluidics constructs. It was shown that the fluid moves up to six times faster in 3D knitted structures containing the composite fibre as compared to equivalent 3D knitted structures made of polyester yarns only, and the flow rate achie ....
Feb 13 2021 Read 2935 Times Researchers at the University of Bristol have developed a way of producing the soft-lithographic moulds used for fabricating microfluidic devices using low-cost 3D-printing techniques. Coupled with the open-source resources developed by the team, this alternative technology has the potential to accelerate uptake and development of on-chip diagnostic techniques in parts of the world where rapid point of care (POC) diagnoses are needed. “Previously, techniques for producing the soft-lithographic scaffolds/moulds (microfluidic channel patterns) were time-consuming and extremely expensive, while other low-cost alternatives were prone to unfavourable properties. This development could put Lab-On-a-Chip prototyping into the hands of researchers and clinicians who know the challenges best, in particular those in resource-limited settings, where rapid diagnostics may often have the greatest impact,” said the study’s lead author Dr Robert Hughes. ....
Scientific breadboard, basically, to make our own chips. each one of these components locks onto a lego piece, and inside is a single feature of a mic microfluidic circuit. you put your feature together for whatever you might need. people who need to test blood for all different kinds of things. this is a crucial ingredient to that. absolutely. so if you have this sort of kit, you can offer blood testing anywhere in the world in places where they typically couldn t. cholesterol, heart disease, diabetes, the biggest killers, really. so when you look at something like this, technology that costs half a million dollars. and very good technology. these are legos that you ve made yourself with kids toys, essentially. how much does a kit like this cost, just for sake of comparison? the microfluidic kit, that s about $150. ....