During their 147 seasons in the National League, 1876-2022, the Cubs used exactly 2,200 different players.
853, or 38.8 percent, hit at least 1 home run as a Cub: 753 position players and 100.
A previous post looked at some of the longest batting streaks by Cubs other than hits and home runs, including Hank Sauer scoring runs in 15 games in a row, Stan Hack making singles in 22 straight.