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Neoadjuvant immunotherapy 'the new standard' for resectable stage III melanoma

CHICAGO — Individuals with resectable stage III melanoma derived significant EFS benefits with neoadjuvant immunotherapy compared with standard treatment, results from a randomized phase 3 trial presented at ASCO Annual Meeting showed.Study participants who received neoadjuvant nivolumab (Opdivo, Bristol Myers Squibb) plus ipilimumab (Yervoy, Bristol Myers Squibb) prior to therapeutic lymph ....

United States , Julier Gralow , Michaelc Lowe , Byjosh Friedman , Emory University School Of Medicine , Bristol Myers Squibb , Netherlands Cancer Institute , International Neoadjuvant Melanoma Consortium , Emory University School ,

Major pathologic response to neoadjuvant pemb

<p style="text-align:start">In exploratory analyses of results from the SWOG S1801 trial in patients with stage III-IV resectable melanoma, researchers saw a major pathologic response in more than half of surgical specimens taken from patients who had been treated with neoadjuvant (pre-operative) pembrolizumab.&nbsp;These and other results of the analyses are presented as a proffered paper (Abstract LBA48) at the European Society of Medical Oncology (ESMO) Congress 2023 in Madrid, Spain, on Monday, October 23, by Sapna P. Patel, MD, chair of the SWOG melanoma committee and associate professor of melanoma medical oncology at the University of Texas MD Anderson Cancer Center.</p>
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United States , Vernonk Sondak , Michaelc Lowe , Aparna Hegde , Johnm Kirkwood , Kaiser Permanente , Thach Giao Truong , Elizabethi Buchbinder , Larissa Korde , G Paul Wright , Phyllis Gyorkey , Antoni Ribas , Victorg Prieto , Sapnap Patel , Megan Othus , Kari Kendra , Elad Sharon , John Hyngstrom , Sunandana Chandra , Craig Devoe , Data Management Center , Moffitt Cancer Center , University Of Utah Huntsman Cancer Institute , National Institutes Of Health , National Clinical Trials Network , Dana Farber Cancer Institute Harvard Center ,