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Novel Drug Prevents Amyloid Plaques, a Hallmark of Alzheimer's Disease


Novel Drug Prevents Amyloid Plaques, a Hallmark of Alzheimer’s Disease
In animal models, the new compound modulated a key enzyme, reducing or eliminating production of problematic protein fragments; human clinical trials needed
March 02, 2021
 |  Scott LaFee
News release
Amyloid plaques are pathological hallmarks of Alzheimer’s disease (AD) clumps of misfolded proteins that accumulate in the brain, disrupting and killing neurons and resulting in the progressive cognitive impairment that is characteristic of the widespread neurological disorder.
In a new study, published March 2, 2021 in the
Journal of Experimental Medicine (JEM), researchers at University of California San Diego School of Medicine, Massachusetts General Hospital and elsewhere have identified a new drug that could prevent AD by modulating, rather than inhibiting, a key enzyme involved in forming amyloid plaques. ....

San Diego , United States , New Hampshire , University Of California San Diego , Douglas Galasko , Kevind Rynearson , Brian Spencer , Jazmin Florio , Carlos Arias , Roberta Rissman , Gopal Thinakaran , Yuhuan Xie , Graham Johnson , Jiunnh Lin , Michael Mante , Mariko Sawa , Olga Prikhodko , Rudolph Tanzi , Moorthi Ponnusamy , Yann Becker , Bahar Salehi , Stevenk Duddy , Williamc Mobley , Stevenl Wagner , Phuong Nguyen , Centers For Disease ,

Novel Drug Prevents Amyloid Plaques, a Hallmark of Alzheimer's Disease

Novel Drug Prevents Amyloid Plaques, a Hallmark of Alzheimer's Disease
scienceblog.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from scienceblog.com Daily Mail and Mail on Sunday newspapers.

San Diego , United States , New Hampshire , University Of California San Diego , Douglas Galasko , Kevind Rynearson , Brian Spencer , Jazmin Florio , Carlos Arias , Roberta Rissman , Gopal Thinakaran , Yuhuan Xie , Graham Johnson , Jiunnh Lin , Michael Mante , Mariko Sawa , Olga Prikhodko , Rudolph Tanzi , Moorthi Ponnusamy , Yann Becker , Bahar Salehi , Stevenk Duddy , Williamc Mobley , Stevenl Wagner , Phuong Nguyen , Centers For Disease ,