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Omics Technology drives Chemical Safety Assessments

New Birmingham spinout company Michabo Health Science Ltd, which aims to provide fast, reliable predictions of whether chemicals are potentially hazardous to human health or the environment, will use methods developed by researchers from the University’s School of Biosciences to assess chemical safety without the need for vertebrate animal testing. Click to read more. ....

John Colbourne , Mark Viant , University School Of Biosciences , Michabo Health Science Ltd , University Of Birmingham Enterprise Ltd , Michabo Health Science , New Birmingham , Professor Mark Viant , Professor John Colbourne , Environmental Genomics , Health Science , Birmingham Enterprise Ltd ,

Fruit fly research part of effort to protect human health from toxic chemicals

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IMAGE: Robert Anholt and Trudy Mackay in a lab holding a test tube containing Drosophila melanogaster, the common fruit fly.
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Credit: Clemson University College of Science
Researchers Trudy Mackay and Robert Anholt of the Clemson University Center for Human Genetics have joined forces with an international consortium intended to drive research that will shape regulation and policy on chemical safety without the use of animal testing.
Mackay, an internationally renowned scientist and director of the Center for Human Genetics (CHG), will team with Anholt to explore the genetic underpinnings of susceptibility to environmental toxicants using Drosophila melanogaster, the common fruit fly. ....

United States , United Kingdom , Baden Wuberg , John Colbourne , Karlsruher Institut , Robert Anholt , Trudy Mackay , Genetic Reference Panel , Michabo Health Science Ltd , European Commission Horizon , University Of Birmingham , Clemson University College Of Science , Clemson University Research Foundation , Clemson University Center , Clemson Division Of Research , Indiana University , University Of Oxford , College Of Science , European Commission , Fundacio Centre De Regulacio Genomica , Greenwood Sc Genetic Center , Cell Networks , Acondicionamieto Tarrasense Association , Researchers Trudy Mackay , Human Genetics , Distinguished Professor ,

Precision Toxicology consortium to protect human health from effects of harmful chemicals

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A major research project to shape regulation and policy on chemical safety without the use of animal testing has been launched with the aid of €19.3M funding from the European Commission.
Led by the University of Birmingham and involving 15 European and US organisations, PrecisionTox aims to protect human health from the toxic effects of chemicals found in people s homes, food and the environment.
The consortium will use genetics, genomics, metabolomics and the study of evolution to investigate the toxicity of hundreds of chemicals and explore how they disrupt the biological processes that are fundamental to health. Combined with law, these approaches will open up a new field of precision toxicology that will transform approaches to chemical safety management in the same way that precision medicine is informing healthcare. In particular, it is expected that precision toxicology will be instrumental in shaping policy and regulation of this field. ....

John Colbourne , Karlsruher Institut , Umweltforschung Gmb , Richard Fuller , Acondicionamiento Tarrasense Associacion , Indiana University , Michabo Health Science Ltd , University Of Oxford , Fundacio Centre De Regulacio Genomics , European Commission , University Of Birmingham , Cell Networks Gmb , Centre For Precision Toxicology , Clemson University , Lancet Commission , University Of Heidelberg , Pure Earth , Grant Agreement , Data Commons , Helmholtz Zentrum , Umweltforschung Gmbh , Cell Networks Gmbh , Fertilizers Pest Management , Ecology Environment , Molecular Biology , Pollution Remediation ,