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Restoring brain pathways to fight opioid addiction

Medical University of South Carolina scientists report in Neuron that they have uncovered a way to restore an opioid-weakened brain pathway in a preclinical model. ....

James Otis , National Institute On Drug Abuse , University Of South Carolina , National Institutes Of Health , South Carolina , National Institute , Drug Abuse , National Institutes , Drug Abuse , Health Care , Substance Use Disorder ,

NIH grant boosts research on biofilm dispersal in wound infections

Most chronic wound infections share one thing in common: the presence of biofilms, which are composed of many different microorganisms that congregate as a mass, usually on some type of surface such as a wound bed. ....

United States , Kendra Rumbaugh , National Institute Of Allergy , Texas Tech University Health Sciences Center , National Institutes Of Health , School Of Medicine Department Surgery , Tech University Health Sciences , National Institute , Infectious Diseases , National Institutes , Health Care , Immune System , Infectious Diseases ,

Ultrahigh-spatial-resolution PCD-CT improves assessment of coronary artery disease

Ultrahigh-spatial-resolution photon-counting detector CT improved assessment of coronary artery disease (CAD), allowing for reclassification to a lower disease category in 54% of patients, according to a new study published today in Radiology, a journal of the Radiological Society of North America. ....

United States , Tomasso Gori , Dirk Graafen , Stefanie Bockius , Moritzc Halfmann , Larissa Kavermann , Tilman Emrich , Nicola Fink , U Joseph Schoepf , Jens Ricke , Geralds Laux , Akos Varga Szemes , Radiological Society Of North America , University Medical Center Mainz , University Of South Carolina , Radiological Society , North America , Medical University , South Carolina , Spatial Resolution Photon Counting Detector , Coronary Artery Disease , Stenosis Assessment , Michaela Hell ,

Study discovers link between a breakdown product from excess niacin and heart disease

Cleveland Clinic researchers have identified a new pathway that contributes to cardiovascular disease associated with high levels of niacin, a common B vitamin previously recommended to lower cholesterol. ....

United States , Stanley Hazen , Jan Bleeksma , Marc Ferrell , Vascular Thoracic Institute , National Institutes Of Health , Human Health , Cleveland Clinic Lerner Research Institute , Cleveland Clinic Center , Metabolic Sciences , Cleveland Clinic , Lerner Research Institute , Co Section Head , Preventive Cardiology , Jan Bleeksma Chair , Vascular Cell Biology , Case Western Reserve University , Medical Scientist Training Program , National Institutes , Heart Disease , Blood Vessels , Cardiovascular Disease , Cell Biology , Heart Attack , Inflammatory Disease , Vitamin B ,

Dietary protein overload linked to increased atherosclerosis risk

University of Pittsburgh School of Medicine researchers discovered a molecular mechanism by which excessive dietary protein could increase atherosclerosis risk. ....

United States , Divya Kapoor , Ismail Sergin , Jeremiah Stitham , Babak Razani , Eman Yousif , Alan Fappi , Marco Sardiello , Jaehyung Cho , Joel Schilling , Abhinav Diwan , Yu Sheng Yeh , Nathan Stitziel , Vasavi Shabrish , Irfan Lodhi , Slava Epelman , Xiangyu Zhang , Bettina Mittendorfer , Jin Jeong , Astrid Rodriguez Velez , Arif Yurdagul Jr , Ali Javaheri , University Of Toronto , Washington University School Of Medicine , University Of Pittsburgh School Medicine , University Of Pittsburgh ,