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Many Patients With Advanced MCC Not Receiving Immunotherapy

Despite improved survival rates and guideline recommendations, many eligible patients with metastatic Merkel cell carcinoma are not receiving immunotherapy. ....

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Adjuvant nivolumab may be promising for treatment of completely resected Merkel cell carcinoma

1. Disease-free survival at 24 months was 84% in the nivolumab group compared to 73% in the observation group. 2. Grade 3-4 adverse events were more common in the nivolumab group, however, there were no reported deaths. Evidence Rating Level: 1 (Excellent) Study Rundown: Merkel cell carcinoma (MCC), an aggressive skin cancer, poses a clinical ....

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Comparison of surgical modalities in the treatment of Merkel Cell Carcinoma

1. Mohs micrographic surgery was associated with significantly higher survival rates for patients with T1/T2 Merkel cell carcinoma with pathologically confirmed negative lymph nodes compared to other surgical modalities (i.e., wide local excision and narrow-margin excision). 2. Mohs micrographic surgery may be a more effective treatment for primary Merkel cell carcinoma than conventional wide-local excision. ....

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