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Decoded: How different immune cells respond to Covid infection


Decoded: How different immune cells respond to Covid infection
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IANS
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Decoded: How different immune cells respond to Covid infection. Image Source: IANS News
London, April 21 : Researchers have identified differences in the immune response to Covid-19, between people with no symptoms, compared to those suffering a more serious reaction to the virus.
The differences could help explain serious lung inflammation and blood clotting symptoms, and could be used to identify potential targets for developing therapies.
The study, published in the journal Nature Medicine, found increased levels of B cells that produce antibodies that are found in mucus passages, such as the nose, in people with no symptoms. ....

United Kingdom , City Of , Menna Clatworthy , University Of Cambridge , Nature Medicine , Translational Immunology , ஒன்றுபட்டது கிஂக்டம் , நகரம் ஆஃப் , மென்னா கிளட்வ்வ்ர்த்தி , பல்கலைக்கழகம் ஆஃப் கேம்பிரிட்ஜ் , இயற்கை மருந்து , மொழிபெயர்ப்பு நோயெதிர்ப்பு ,

Explained: How different immune cells respond to Covid infection


Explained: How different immune cells respond to Covid infection
The team performed single-cell sequencing from 800,000 individual immune cells, along with detailed analysis of cell surface proteins
Wednesday April 21, 2021 8:22 PM, IANS
London: Researchers have identified differences in the immune response to Covid-19, between people with no symptoms, compared to those suffering a more serious reaction to the virus.
The differences could help explain serious lung inflammation and blood clotting symptoms, and could be used to identify potential targets for developing therapies.
The study, published in the journal Nature Medicine, found increased levels of B cells that produce antibodies that are found in mucus passages, such as the nose, in people with no symptoms. ....

United Kingdom , City Of , Menna Clatworthy , University Of Cambridge , Immune Response , Nature Medicine , Translational Immunology , ஒன்றுபட்டது கிஂக்டம் , நகரம் ஆஃப் , மென்னா கிளட்வ்வ்ர்த்தி , பல்கலைக்கழகம் ஆஃப் கேம்பிரிட்ஜ் , நோய் எதிர்ப்பு சக்தி பதில் , இயற்கை மருந்து , மொழிபெயர்ப்பு நோயெதிர்ப்பு ,

Differing immune responses discovered in asymptomatic cases vs those with severe COVID-19


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The largest study of its type in the UK has identified differences in the immune response to COVID-19, between people with no symptoms, compared to those suffering a more serious reaction to the virus.
Researchers from the Wellcome Sanger Institute, Newcastle University, University College London, University of Cambridge, EMBL s European Bioinformatics Institute (EMBL-EBI) and their collaborators within the Human Cell Atlas initiative, found raised levels of specific immune cells in asymptomatic people. They also showed people with more serious symptoms had lost these protective cell types, but gained inflammatory cells. These differences in the immune response could help explain serious lung inflammation and blood clotting symptoms, and could be used to identify potential targets for developing therapies. ....

United Kingdom , United States , City Of , Emily Stephenson , Menna Clatworthy , Fernandoj Calero Nieto , Michaeld Morgan , Sarah Teichmann , Zewen Kelvin Tuong , Gary Reynolds , Karsten Bach , John Marioni , Aviv Regev , Waradon Sungnak , Rachela Botting , Emuzlifah Haniffa , Research Excellence Framework , University College London , Broad Institute , Cancer Research United Kingdom Cambridge Institute , Head Of Research , Senior Group Leader , Wellcome Sanger Institute Associate Faculty , University Of Cambridge , Newcastle University , European Bioinformatics Institute ,