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Non-small cell lung cancer (NSCLC) patients in stage IV of the disease are commonly diagnosed with bone metastases, which is the leading cause of death in NSCLC patients. Once the cancer cells have metastasised, the disease is considered incurable and palliative treatment such as radiotherapy given as 8 Gy in a single fraction or 25 Gy in 5 fractions is one of the most common treatment options to provide relief from pain. Recent, clinical trials have shown that if a limited number of metastatic bone lesions, in their early stage of metastases (called, oligometastasis) treated with very high, stereotactic doses such as 30 Gy in 3 fractions or 16-20 Gy in single fraction could increase survival without the progression of the diseases as well as overall survival of these patients. NSCLC patients undergo 18F-fluorodeoxyglucose (FDG) – positron emission tomography (PET)/ computer tomography (CT), in short, FDG-PET/CT imaging for identification of stage and progression of the disease as we

Medical image processingImage segmentation