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Chinese Registry Supports Prolonged DAPT Following PCI for ACS

May 03, 2021
Long-term dual antiplatelet therapy (DAPT) reduces ischemic events without a trade-off in bleeding compared with shorter durations among ACS patients who undergo PCI, according to new registry data from China.
The findings, released at the virtual Society for Cardiovascular Angiography and Interventions (SCAI) 2021 meeting, are slightly out of step with the TWILIGHT ACS substudy, which indicated a shorter duration of DAPT followed by ticagrelor monotherapy lowers bleeding risk in these patients without increasing ischemic events. In the Chinese registry, DAPT primarily consisted of clopidogrel and aspirin.
“To the best of our knowledge, this is the first report investigating the feasibility and safety of long-term DAPT for high-risk ‘TWILIGHT-like’ patients with ACS treated with DES,” Hao-Yu Wang, MD (Fuwai Hospital, Beijing, China), said in his presentation. “These results suggested that prolonged DAPT in ACS patients who present with a particul ....

Medstar Washington Hospital Center , District Of Columbia , United States , Zhaoyu Wang , Bonnie Weiner , David Cox , Md Brown University , Md Medstar Washington Hospital Center , Md Lehigh Valley Health Network , Society For Cardiovascular Angiography , Cardiovascular Angiography , Fuwai Hospital , Cardiovascular Interventions , Lehigh Valley Health Network , Brown University , Ron Waksman , Saint Vincent Hospital , மெட்ஸ்டார் வாஷிங்டன் மருத்துவமனை மையம் , மாவட்டம் ஆஃப் கொலம்பியா , ஒன்றுபட்டது மாநிலங்களில் , போனி வீனர் , டேவிட் காக்ஸ் , ம்ட் பழுப்பு பல்கலைக்கழகம் , ம்ட் மெட்ஸ்டார் வாஷிங்டன் மருத்துவமனை மையம் , சமூகம் க்கு இருதய ஆஞ்சியோகிராபி , இருதய ஆஞ்சியோகிராபி ,