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Scientists Improve Contrast In Noninvasive Imaging of Cancer Cells, NUST MISIS reports

Scientists Improve Contrast In Noninvasive Imaging of Cancer Cells, NUST MISIS reports
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MOSCOW, May 17, 2021 /PRNewswire/
A Russian-German research team has come up with a new technique for magnetic resonance imaging of cancer cells. The study, published in Pharmaceutics, shows that heterologous expression of encapsulin systems from Quasibacillus thermotolerans with functional cargo proteins and iron transporter leads to increased contrast in MRI imaging of mammalian tumor cells.
Currently, the primary method of live-cell imaging is direct labeling of cells with a probe or contrast agent before transplantation. However, any synthetic contrast agent for cell labeling has a critical drawback it dilutes as the cells divide, which leads to loss of the signal after several cycles of divisions. In contrast, genetically encoded reporters propagate to daughter cells with each cell division. Moreover, their si ....

Maxim Abakumov , Technology Misi , Biomedical Nanomaterials Laboratory , Helmholtz Center Munich , National University Of Science , Technical University , V Serbsky National , Medicinal Nanobiotechnology Department , Nanomaterials Laboratory , Russian National Research Medical , National Medical , Russian National Research Medical University , National University , The National University Of Science And Technology Misis , தொழில்நுட்பம் மிசி , உயிர் மருத்துவ நானோ பொருட்கள் ஆய்வகம் , தேசிய பல்கலைக்கழகம் ஆஃப் அறிவியல் , தொழில்நுட்ப பல்கலைக்கழகம் , நானோ பொருட்கள் ஆய்வகம் , தேசிய மருத்துவ , ரஷ்ய தேசிய ஆராய்ச்சி மருத்துவ பல்கலைக்கழகம் , தேசிய பல்கலைக்கழகம் ,

Scientists Improve Contrast In Noninvasive Imaging of Cancer Cells, NUST MISIS reports

Scientists Improve Contrast In Noninvasive Imaging of Cancer Cells, NUST MISIS reports
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Maxim Abakumov , Technology Misi , Biomedical Nanomaterials Laboratory , Helmholtz Center Munich , National University Of Science , Technical University , V Serbsky National , Medicinal Nanobiotechnology Department , Nanomaterials Laboratory , Russian National Research Medical , National Medical , Russian National Research Medical University , National University , தொழில்நுட்பம் மிசி , உயிர் மருத்துவ நானோ பொருட்கள் ஆய்வகம் , தேசிய பல்கலைக்கழகம் ஆஃப் அறிவியல் , தொழில்நுட்ப பல்கலைக்கழகம் , நானோ பொருட்கள் ஆய்வகம் , தேசிய மருத்துவ , ரஷ்ய தேசிய ஆராய்ச்சி மருத்துவ பல்கலைக்கழகம் , தேசிய பல்கலைக்கழகம் ,