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Thylacine Biotherapeutics Licenses Novel Antiviral Peptide Platform from Columbia University

/PRNewswire/ Thylacine Biotherapeutics Inc. ("Thylacine Bio"), a privately held biotech company dedicated to combating infectious disease, announced today. ....

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CUIMC Update - May 18, 2022

View the CUIMC Update, a weekly e-newsletter featuring medical center news and the accomplishments of our faculty, staff, and trainees. ....

New York , United States , Columbia University , Washington Heights , H Thomas Lee , Erika Berman Rosenzweig , Gabriel Perreault , Sarah Richardson , Daniela Jodorkovsky , Leah Estrada , Christoph Kellendonk , Ashley Boyce , Ivonne Ramirez , Tamara Marie , Adam David Griesemer , Ryuichi Shimada , Matteo Porotto , Kenrick Cato , Elizabeth Oelsner , Benjamin Lebwohl , Tonya Richards , Ritad Zielstorff , Mary Ann Carlese , Sarah Rossetti , Sherley Desulme Willis , Blood Institute For Proteomics ,

Researchers improve method to inhibit viruses that cause childhood respiratory infections

By engineering a short chunk of protein, or peptide, that can prevent the attachment of human parainfluenza viruses to cells, researchers have improved a method in rodent models intended to help keep children healthy. ....

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Scientists develop better way to block viruses causing respiratory infections in children

Scientists develop better way to block viruses causing respiratory infections in children
ANI |
Updated: May 11, 2021 11:29 IST
Washington [US], May 11 (ANI): Researchers have improved a method in rodent models intended to help keep children healthy by engineering a short chunk of protein, or peptide, that can prevent the attachment of human parainfluenza viruses to cells.
Human parainfluenza viruses, or HPIVs, are the leading cause of childhood respiratory infections, responsible for 30 per cent to 40 per cent of illnesses like croup and pneumonia. The viruses also affect the elderly and people with compromised immune systems. The researchers published their findings in the Journal of the American Chemical Society. ....

United States , Anne Moscona , Sam Gellman , University Of Wisconsin , Journal Of The American Chemical Society , Matteo Porotto At Columbia University , American Chemical , Matteo Porotto , Columbia University , Victor Outlaw , ஒன்றுபட்டது மாநிலங்களில் , சாம் கெல்ள்மான் , பல்கலைக்கழகம் ஆஃப் விஸ்கான்சின் , இதழ் ஆஃப் தி அமெரிக்கன் இரசாயன சமூகம் , அமெரிக்கன் இரசாயன , கொலம்பியா பல்கலைக்கழகம் ,

Scientists develop better way to block viruses that cause childhood respiratory infections

Date Time
Scientists develop better way to block viruses that cause childhood respiratory infections
The anti-viral peptide is made up of three corkscrews (in green), which lock around the virus’s fusion protein (in orange) to prevent the virus from entering cells. The Gellman lab added unique beta amino acids to the peptide (in purple) in a way that didn’t interfere with this crucial interaction and made the peptide more stable. Images by Victor Outlaw.
By engineering a short chunk of protein, or peptide, that can prevent the attachment of human parainfluenza viruses to cells, researchers have improved a method in rodent models intended to help keep children healthy. ....

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