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Hope for sickle cell disease patients in new treatment technology

For people with sickle cell disease, their red blood cells usually look like a C-shaped farm tool called a sickle. ....

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Experimental gene therapy reverses sickle cell disease for three years

Experimental gene therapy reverses sickle cell disease for three years
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CRISPR technology to cure sickle cell disease at UIC

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University of Illinois Chicago is one of the U.S. sites participating in clinical trials to cure severe red blood congenital diseases such as sickle cell anemia or Thalassemia by safely modifying the DNA of patients blood cells.
The first cases treated with this approach were recently published in an article co-authored by Dr. Damiano Rondelli, the Michael Reese Professor of Hematology at the UIC College of Medicine. The article reports two patients have been cured of beta thalassemia and sickle cell disease after their own genes were edited with CRISPR-Cas9 technology. The two researchers who invented this technology received the Nobel Prize in Chemistry in 2020. ....

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