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Ambys Medicines - AlleyWatch

Ambys Medicines is a biotechnology company focused on discovering and developing regenerative and restorative therapies. Founded by Holger Willenbring, Juan Carlos Izpisua Belmonte, Markus Grompe, and Martin Burke in 2018, Ambys Medicines is backed by Takeda, Alexandria Venture Investments, Takeda Ventures, Inc., Schroders Capital, and Third Rock Ventures and is headquartered in South San Francisco. ....

Weekly Notable Startup Funding Report , Ambys Medicines , Holger Willenbring , Juan Carlos Izpisua Belmonte , Markus Grompe , Martin Burke ,

New approach to gene therapy uses common pain reliever to fight against genetic diseases


New approach to gene therapy uses common pain reliever to fight against genetic diseases
Researchers have developed a new approach to gene therapy that leans on the common pain reliever acetaminophen to force a variety of genetic diseases into remission.
A paper published in
Science Translational Medicine describes how the novel technique successfully treated the blood-clotting disorder hemophilia and the debilitating metabolic disease known as phenylketonuria, or PKU, in mice.
The approach uses a benign lentivirus to both correct disease-causing mutations and to insert a new gene that makes liver cells immune to the potentially toxic effects of acetaminophen. The latter enables treated cells to survive and kills off untreated cells when they re repeatedly exposed to the over-the-counter medication that s also known by the brand name Tylenol. This allows the treated cells to multiply and creates a greater portion of liver cells being corrected. ....

United States , Markus Grompe , Emily Henderson , Oregon Health Science University School Of Medicine , Science Translational Medicine , Oregon Health , Science University School , ஒன்றுபட்டது மாநிலங்களில் , எமிலி ஹென்டர்சன் , ஓரிகந் ஆரோக்கியம் அறிவியல் பல்கலைக்கழகம் பள்ளி ஆஃப் மருந்து , அறிவியல் மொழிபெயர்ப்பு மருந்து , ஓரிகந் ஆரோக்கியம் , அறிவியல் பல்கலைக்கழகம் பள்ளி ,