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Merck drug data suggest 'new direction' for rare blood vessel disease

BioPharma ....

Marius Hoeper , Merck Research Laboratories , Hannover Medical School , Merck Co , New England Journal , Clinical Trials ,

Merck's Investigational Activin Signaling Inhibitor Sotatercept Improved Six-Minute Walk Distance by 40.8 Meters at Week 24 Versus Placebo in Adults with Pulmonary Arterial Hypertension on Background Therapy

Sotatercept demonstrated statistically significant improvements in 8 of 9 secondary measures, including reduction in risk of clinical worsening or deathResults presented today at ACC.23/WCC and published in The New England Journal of MedicineRAHWAY, N.J. (BUSINESS WIRE) $MRK #MRK Merck (NYSE: MRK), known as MSD o. ....

United States , Julie Cunningham , Marius Hoeper , Peter Dannenbaum , Damini Chokshi , Merck Research Laboratories , Hannover Medical School , Drug Administration , Statement Of Merck Co Inc , Exchange Commission , Merck Co Inc , European Medicines Agency , Bristol Myers Squibb , Acceleron Pharma Inc , New England Journal , Merck Research , Physical Impacts , Cardiopulmonary Symptoms , Emotional Impacts , Breakthrough Therapy Designation , Orphan Drug , Priority Medicines , Acceleron Pharma , Bristol Myers , Looking Statement , Securities Litigation Reform Act ,

Merck (MRK) Announces Sotatercept Improved Six-Minute Walk Distance by 40.8 Meters at Week 24 Versus Placebo in Adults with Pulmonary Arterial Hypertension on Background Therapy

Merck (MRK) Announces Sotatercept Improved Six-Minute Walk Distance by 40.8 Meters at Week 24 Versus Placebo in Adults with Pulmonary Arterial Hypertension on Background Therapy
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United States , Marius Hoeper , Merck Research Laboratories , Hannover Medical School , New England Journal , Merck Research , Physical Impacts , Cardiopulmonary Symptoms , Emotional Impacts ,

Setting a course for progress in respiratory medicine

On Aug 26, 2022, the European Society of Cardiology and the European Respiratory Society
published new guidelines for the diagnosis and treatment of pulmonary hypertension.
Numerous factors are associated with the development of pulmonary hypertension, which
has an estimated prevalence of around 1% globally, increasing to 10% in individuals
older than 65 years, and is associated with worsening symptoms including dyspnoea,
fatigue, and syncope and substantially increased mortality. The guidelines, which
emphasise the need for earlier detection of pulmonary hypertension and timely referral
of high-risk or complex patients, provide new definitions of pulmonary hypertension,
an updated classification across groups 1–5, new algorithms for detection and treatment,
and tools for risk stratification at diagnosis and follow-up. ....

Xavier Ja , Takashi Kawakami , Marius Hoeper , European Respiratory Society , European Society Of Cardiology , Lancet Commission , Elsevier Ltd , Studio Science Photo Library , European Society , Lancet Respiratory Medicine , View Large , Science Photo ,

Riociguat an Option for Pulmonary Arterial Hypertension When PDE-5 Inhibitors Fail

Riociguat an Option for Pulmonary Arterial Hypertension When PDE-5 Inhibitors Fail
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Mayo Clinic In Rochester , United States , Merck Sharpe , Marius Hoeper , Robert Frantz , Dohme Corp , Bayer Ag , Reuters Health , Hanover Medical School , Lancet Respiratory Medicine , Mayo Clinic , மயோ சிகிச்சையகம் இல் ரோசெஸ்டர் , ஒன்றுபட்டது மாநிலங்களில் , மெர்க் கூர்மையான , ராபர்ட் ஃப்ர்யாஂட்ஸ் , ராய்ட்டர்ஸ் ஆரோக்கியம் , ஹ்யாநவர் மருத்துவ பள்ளி , மயோ சிகிச்சையகம் ,