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Unexpected Variation in Key RNA Gene

Although ribosomal RNA genes were thought to be similar among people, researchers have found that they differed significantly based upon a person’s geographic ancestry. Particularly high variations were found on a segment called 28S rRNA, an essential component of the protein-translating ribosome. While still too early to speculate what these variants mean, the fact that they are conserved by population means their retention is important. ....

United States , Johns Hopkins University , University Of Maryland , Marikki Laiho , Johns Hopkins Kimmel Cancer Center , Maryland Advanced Research Computing Center ,

Genome study reveals unexpected heterogeneity of human ribosomal RNA genes

A genome study undertaken by Johns Hopkins Kimmel Cancer Center researchers to look for variants in a gene considered a fundamental building block for microscopic structures that synthesize proteins took a surprising twist. ....

United States , Johns Hopkins University , University Of Maryland , Marikki Laiho , Emily Henderson , Johns Hopkins Kimmel Cancer Center , Molecular Radiation Sciences , Department Of Radiation Oncology , Maryland Advanced Research Computing Center , Radiation Oncology , Molecular Radiation ,

Genome Study Finds Unexpected Variation in a Fundamental RNA Gene

A genome study undertaken by Johns Hopkins Kimmel Cancer Center researchers to look for variants in a gene considered a fundamental building block for microscop ....

United States , Johns Hopkins University , Eteläuomen Läi , University Of Maryland , Chester Liu , Eetu Eklund , Stephanie Pitts , Rachel Sherman , Johns Hopkins , Brittany Ford , Marikki Laiho , University Of Helsinki , National Cancer Institute , Molecular Radiation Sciences , Johns Hopkins Kimmel Cancer Center , Maryland Advanced Research Computing Center , Department Of Radiation Oncology , National Institute , Radiation Oncology , Wenjun Fan , Rajesh Kumar , General Medical Sciences , Ancer Sidney Kimmel Cancer Center Marikki Laiho Rna Rrna 28s Department Of Radiation Oncology And Molecular Sciences Ancestry Dependent Variants Johns Hopkins , All Journal News , Grant Funded News , Johns Hopkins Medicine ,

Genome Study Finds Unexpected Variation in Fundamental RNA Gene

Unexpected heterogeneity of ribosomal RNA genes in human populations revealed by genome studies suggests potential variation in protein translation by ....

United States , Johns Hopkins University , Eteläuomen Läi , University Of Maryland , Chester Liu , Eetu Eklund , Stephanie Pitts , Rachel Sherman , Johns Hopkins , Brittany Ford , Marikki Laiho , University Of Helsinki , National Cancer Institute , Molecular Radiation Sciences , Johns Hopkins Kimmel Cancer Center , Maryland Advanced Research Computing Center , Department Of Radiation Oncology , National Institute , Genome Project , Johns Hopkins Medicine , Wenjun Fan , Radiation Oncology , Rajesh Kumar , General Medical Sciences ,