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Sagimet Biosciences (SGMT) Presents Preclinical Results Supporting the Therapeutic Potential of its FASN inhibitor in Combination with Semaglutide and a Comprehensive Lipidomic Analysis

Sagimet Biosciences (SGMT) Presents Preclinical Results Supporting the Therapeutic Potential of its FASN inhibitor in Combination with Semaglutide and a Comprehensive Lipidomic Analysis
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Sagimet Biosciences Presents Preclinical Results Supporting the Therapeutic Potential of its FASN inhibitor in Combination with Semaglutide and a Comprehensive Lipidomic Analysis of Interim FASCINATE-2 Data at AASLD - The Liver Meeting® 2023

Combination treatment of a FASN inhibitor with semaglutide, a GLP-1 receptor agonist, improved several biomarkers associated with NASH in a mouse model and showed a significant improvement in liver. ....

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Sagimet Biosciences Announces Acceptance of Two Abstracts at AASLD

Sagimet Biosciences Announces Acceptance of Two Abstracts at AASLD
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Sagimet to Present Phase 2 Data on Lead Candidate TVB-2640 at The International Liver Congress™ 2021 (EASL)

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SAN MATEO, Calif., April 23, 2021 /PRNewswire/ Sagimet Biosciences, a clinical-stage biotechnology company focused on developing a portfolio of internally-discovered, selective fatty acid synthase (FASN) inhibitors, announced today that additional clinical and biomarker research on its lead product candidate, currently being evaluated as a potential treatment for nonalcoholic steatohepatitis (NASH), will be shared via a poster presentation at The International Liver Congress™ 2021 (EASL), which will be held virtually from June 23-26, 2021.
Marie O Farrell, PhD, will present results from an ongoing Phase 2 clinical trial of TVB-2640 in NASH patients in the poster entitled Analysis of non-invasive biomarker tests in the Phase 2 FASCINATE-1 Study of FASN Inhibitor TVB-2640. ....

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