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DNA shed from colon cancers into bloodstream successfully guides chemotherapy after surgery

DNA shed from colon cancers into bloodstream successfully guides chemotherapy after surgery
miragenews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from miragenews.com Daily Mail and Mail on Sunday newspapers.

United States , Janine Ptak , Cristian Tomasetti , Suzanne Kosmider , Kamel Lahouel , S Marion Harris , Nickolas Papadopoulos , Jeremy Shapiro , Anne Mclachlan , Lisa Dobbyn , Anne Marie Lennon , Natalie Silliman , Johns Hopkins , Yuxuan Wang , Ralph Hruban , Maria Popoli , Theresa Hayes , Belinda Lee , Joshua Cohen , Margaret Lee , Bert Vogelstein , Sam Harris , Kenneth Kinzler , James Lynam , Adnan Khattak , Peter Gibbs ,

DNA Shed From Colon Cancers Into Bloodstream Guide Chemotherapy

DNA Shed From Colon Cancers Into Bloodstream Guide Chemotherapy
miragenews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from miragenews.com Daily Mail and Mail on Sunday newspapers.

United States , Janine Ptak , Cristian Tomasetti , Suzanne Kosmider , Kamel Lahouel , S Marion Harris , Nickolas Papadopoulos , Jeremy Shapiro , Anne Mclachlan , Lisa Dobbyn , Anne Marie Lennon , Natalie Silliman , Johns Hopkins , Elizabeth Cook , Yuxuan Wang , Ralph Hruban , Maria Popoli , Theresa Hayes , Belinda Lee , Joshua Cohen , Margaret Lee , Bert Vogelstein , Sam Harris , Kenneth Kinzler , James Lynam , Adnan Khattak ,

Hopkins-led research team takes gene mutation detection in blood to the next level

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IMAGE: New SaferSeqS technology detects rare mutations in blood in a highly efficient manner and reduces the error rate.
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Credit: Elizabeth Cooke
Next-generation gene sequencing (NGS) technologies in which millions of DNA molecules are simultaneously but individually analyzed theoretically provides researchers and clinicians the ability to noninvasively identify mutations in the blood stream. Identifying such mutations enables earlier diagnosis of cancer and can inform treatment decisions. Johns Hopkins Kimmel Cancer Center researchers developed a new technology to overcome the inefficiencies and high error rates common among next-generation sequencing techniques that have previously limited their clinical application.
To correct for these sequencing errors, the research team from the Ludwig Center and Lustgarten Laboratory at the Johns Hopkins Kimmel Cancer Center developed SaferSeqS (Safer Sequencing System), a major improvement ....

United States , Janine Ptak , Cristian Tomasetti , Maria Popoli , Joshua Cohen , Jonathanc Dudley , Nickolas Papadopoulos , Bert Vogelstein , Johns Hopkins Christopher Douville , Kenneth Kinzler , Peter Gibbs , Lisa Dobbyn , Natalie Silliman , Johns Hopkins University , Translational Research Grant , National Institutes Of Health , John Templeton Foundation , Lustgarten Foundation For Pancreatic Cancer Research , Dk Ludwig Fund For Cancer Research , Lustgarten Laboratory , Johns Hopkins Kimmel Cancer Center , Sciences In Jan , Eliza Hall Institute Of Medical Research , Ludwig Center , Marcus Foundation , University Of Melbourne ,