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ATH434 protects brain cells and improves motor function in Parkinsonian disorder


ATH434 protects brain cells and improves motor function in Parkinsonian disorder
Oral presentation at the American Academy of Neurology
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MELBOURNE, Australia
 , April 21, 2021 /PRNewswire/ Alterity Therapeutics (ASX: ATH,NASDAQ: ATHE) ( Alterity or the Company ) today announced an oral presentation of expanded animal data to support the commercialisation of its lead compound ATH434 in clinical development for the treatment of Parkinsonian disorders, at the American Academy of Neurology (AAN) virtual annual meeting.
The AAN conference, held this week, is the world s preeminent clinical and scientific conference in the neurology space.  The presentation titled
ATH434 Preserves Dopaminergic Neurons, Reduces α-synuclein Oligomerization, and Improves Motor Function in a Transgenic Murine Multiple System Atrophy Model ....

United States , Nadia Stefanova , Margaret Bradbury , Antonio Heras Garvin , David Stamler , Violetta Refolo , University Of Innsbruck , Professor Of Translational Neurodegeneration Research , European Commission , American Academy Of Neurology , Securities Exchange , American Academy , Dopaminergic Neurons , Improves Motor Function , Transgenic Murine Multiple System Atrophy , Multiple System Atrophy , Chief Executive Officer , Translational Neurodegeneration Research , Medical University , Progressive Supranuclear Palsy , System Atrophy , Securities Act , Securities Exchange Act , ஒன்றுபட்டது மாநிலங்களில் , மார்கரெட் பிராட்பரி , பல்கலைக்கழகம் ஆஃப் இந்ந்‌ஸ்ப்ரக் ,

Alterity Therapeutics announces funding from Michael J. Fox Foundation for ATH434 dose optimization for Parkinson's disease clinical trials


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NEW YORK, Feb. 9, 2021 /PRNewswire/ Alterity Therapeutics (ASX: ATH,NASDAQ: ATHE) ( Alterity or the Company ) has today announced the award of a grant from The Michael J. Fox Foundation for Parkinson s Research to determine optimal dosing of its lead drug candidate ATH434 for Parkinson s disease (PD) based on imaging of brain iron.
The funding for US$495,000 will be used to evaluate the pharmacologic profile of ATH434 in a primate model to determine the optimal dose of ATH434 in future Parkinson s disease clinical trials.  This is the second grant that Alterity has received from The Michael J. Fox Foundation to support the development of ATH434 in PD. ....

Daniel Claassen , Margaret Bradbury , David Finkelstein , Werner Poewe , David Stamler , Mental Health , European Commission , Nonclinical Development , Florey Institute Of Neuroscience , University Innsbruck , Securities Exchange , Michaelj Fox Foundation , Alterity Therapeutics , Michaelj Fox Foundation For Parkinson Research , Pd Research Laboratory , Chief Executive Officer Dr David Stamler , Multiple System Atrophy , Medical University Innsbruck , Vice President , Associate Professor , Vanderbilt University Medical Center , Florey Institute , Alterity Therapeutics Limited , Progressive Supranuclear Palsy , Disease Statistics , System Atrophy ,