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Toxins from one bacterial species contribute to genetic diversity of others


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A toxin produced by bacteria as a defence mechanism causes mutations in target bacteria that could help them survive, according to a study published today in
eLife.
The finding suggests that competitive encounters between bacterial cells could have profound consequences on the evolution of bacterial populations.
When bacterial cells come into contact, they often produce toxins as a defence mechanism. Although it is known that the bacteria producing these toxins have a competitive advantage, exactly how the toxins affect the recipient cells is less clear.
Undergoing intoxication is not always detrimental for cells - there are scenarios in which encountering a toxin could provide a benefit, such as generating antibiotic resistance, explains lead author Marcos de Moraes, Postdoctoral Scholar at the University of Washington School of Medicine, Seattle, US. We wanted to study the effects of a toxin that alters DNA beyond that of cell death and see how i ....

Joseph Mougous , Emily Packer , University Of Washington , Alice Wallenberg Foundation , University Of Washington School Medicine , Howard Hughes Medical Institute Investigator , Max Planck Society , Howard Hughes Medical Institute , Marcos De Moraes , Postdoctoral Scholar , Washington School , Ddda Producing Burkholderia , Special Issue , Relations Manager , Infectious Disease , Medicine Health , Infectious Emerging Diseases , எமிலி ப்யாகர் , பல்கலைக்கழகம் ஆஃப் வாஷிங்டன் , ஆலிஸ் வாலன்பெர்க் அடித்தளம் , பல்கலைக்கழகம் ஆஃப் வாஷிங்டன் பள்ளி மருந்து , ஹோவர்ட் ஹக்ஸ் மருத்துவ நிறுவனம் புலனாய்வாளர் , ஹோவர்ட் ஹக்ஸ் மருத்துவ நிறுவனம் , மார்கோஸ் டி மரஸ் , போஸ்ட்‌டாக்டொரல் அறிஞர் , வாஷிங்டன் பள்ளி ,