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Chromosomal instability in cancer cells causes DNA damage and promotes invasiveness: Study phys.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from phys.org Daily Mail and Mail on Sunday newspapers.
Study unravels the link between chromosomal instability and cellular senescence Chromosomal instability is a feature of solid tumors such as carcinoma. Likewise, cellular senescence is a process that is highly related to cellular ageing and its link to cancer is becoming increasingly clear. Scientists led by ICREA researcher Dr. Marco Milán at IRB Barcelona have revealed the link between chromosomal instability and cellular senescence. Chromosomal instability and senescence are two characteristics common to most tumors, and yet it was not known how one related to the other. Our studies indicate that senescence may be one of the intermediate links between chromosomal alterations and cancer. ....