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FDA Approval Insights: Nirogacestat in Progressing Desmoid Tumors Requiring Systemic Treatment

Dr Kasper discusses the FDA approval of nirogacestat for patients with progressing desmoid tumors; key efficacy, safety, and quality-of-life outcomes from the pivotal DeFi trial; and findings from an analysis investigating tumor volume and T2 hyperintensity changes with nirogacestat in patients enrolled in DeFi. ....

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Dr Kasper on the Evaluation of Nirogacestat in Desmoid Tumors in the DeFi Trial

Bernd Kasper, MD, PhD, professor, Universitätsmedizin Mannheim, Mannheim, discusses the effect of nirogacestat on tumor volume and T2 hyperintensity in patients with desmoid tumors. ....

Bernd Kasper , Mannheim University Medical Center , Desmoid Tumors , Asco 2023 ,