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Pliant Therapeutics Announces Positive Safety and Exploratory Efficacy Data from Phase 2a INTEGRIS-PSC Clinical Trial of Bexotegrast in Patients with Primary Sclerosing Cholangitis and Suspected Liver Fibrosis

Bexotegrast was well tolerated over 12 weeks of treatment with few discontinuations and no drug-related severe or serious adverse events Bexotegrast reduced both the Enhanced Liver Fibrosis .

United statesChristopher keenanClin gastroenterol hepatolDrug administrationUniversity of miami school medicinePliant therapeutics incEuropean medicines agencyCorporate communicationsEnhanced liver fibrosisChief medical officerMayo scoreDemonstrated antifibrotic activitySuspected moderateSevere liver fibrosisItch numerical rating scaleCynthia levy

Pliant Therapeutics Announces Positive Safety and

Bexotegrast (PLN-74809) was well tolerated over 12 weeks of treatment with few discontinuations and no drug-related severe or serious adverse events .

United statesChristopher keenanClin gastroenterol hepatolUniversity of miami school medicinePliant therapeutics incCorporate communicationsDrug administrationEuropean medicines agencyEnhanced liver fibrosisChief medical officerMayo scoreDemonstrated antifibrotic activitySuspected moderateSevere liver fibrosisItch numerical rating scaleCynthia levy

Evaluating NMR relaxometry for antibody identification

Evaluating NMR relaxometry for antibody identification
europeanpharmaceuticalreview.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from europeanpharmaceuticalreview.com Daily Mail and Mail on Sunday newspapers.

United statesGovernors state universityNorthern illinois universityNorth chicagoChromatogrb biomedGregory websterGiraudeaup benchtopSenior principal research scientist in analyticalSt xavier collegeTime domain nuclear magnetic resonanceInternational pharmaceutical qualityDrug delivery researchAgilent technologiesSenior principal research scientist at abbvieSenior principal research scientistAnalytical research

Assessment of a non-invasive brain pulse monitor

Intracranial pressure monitoring requires placing a hole in the skull through which an invasive pressure monitor is inserted into the brain

Integra lifesciencesBarry dixonActa neurochirBiomed engSiddiqf duralLe rouxRobert tranJacobsen teixeiraPty ltdResearch future fund of the australian governmentKeylead healthBrain trauma foundationBiomedtech horizons programHealth nmoData sharingMedical research future fund

FGF-21 as a potential therapeutic target of NAFLD

The aim of this review is to critically summarize experimental and clinical data of fibroblast growth factor-21 in nonalcoholic fatty liver disease.

China generalWest virginiaUnited statesWest virginianCardiovasc diabetolPhysiol pharmacolZavosc adiponectinZang bing za zhiPablo friasHassani zadehBiochim biophys actaNutrigenet nutrigenomicsMinerva endocrinolJ nutr biochemPhysiol biochemGastroenterol hepatol