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Study identifies APOE4 homozygotes as high-risk group for Alzheimer's disease

Researchers from the Research Area on Neurological Diseases, Neuroscience, and Mental Health at the Sant Pau Research Institute, led by Dr. Juan Fortea, Director of the Memory Unit of the Neurology Service at the same hospital, have found that over 95% of individuals over 65 years old who have two copies of the APOE4 gene -APOE4 homozygotes- show biological characteristics of Alzheimer's pathology in the brain or biomarkers of this disease in cerebrospinal fluid and PET scans.

United-states
Juan-fortea
National-alzheimer-coordinating-center-united-states
Research-area-on-neurological-diseases
Memory-unit-of-the-neurology-service
Mental-health
Sant-pau-research-institute
Research-area
Neurological-diseases
Memory-unit
Neurology-service
Nature-medicine

New discovery offers dietary solution for pulmonary hypertension

Blood vessels in the lungs aren't like the others in the body. This difference becomes clear in pulmonary hypertension, in which only the lungs' blood vessels stiffen progressively, leading to chronic lung disease, heart failure and death.

France
Azur
Aquitaine
Thomas-bertero
Stephen-chan
Vascular-medicine-institute
University-of-pittsburgh-school-medicine
University-of-pittsburgh
Division-of-cardiology
Vitalant-chair
Vascular-medicine
Pulmonary-vascular-biology

Scientists uncover a cell responsible for repairing damaged liver tissue

A type of cell responsible for repairing damaged liver tissue has been uncovered for the first time by a team of scientists, including Professor Rajiv Jalan (UCL Liver & Digestive Health).

Glasgow
Glasgow-city
United-kingdom
Cambridge
Cambridgeshire
Texas
United-states
Edinburgh
City-of
Neil-henderson
Rajiv-jalan
Wellcome

New brain connectivity maps offer insights into human consciousness

In a paper titled, "Multimodal MRI reveals brainstem connections that sustain wakefulness in human consciousness," published today in Science Translational Medicine, a group of researchers at Massachusetts General Hospital, a founding member of the Mass General Brigham healthcare system, and Boston Children's Hospital, created a connectivity map of a brain network that they propose is critical to human consciousness.

Boston
Massachusetts
United-states
Brian-edlow
Hannah-kinney
Neurology-at-harvard-medical-school
Research-scholar
Harvard-medical-school
Chen-institute
Harvard-ascending-arousal-network-atlas
Science-translational-medicine
Massachusetts-general-hospital

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