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RNA-binding plus ribosomal proteins block c-Myc in lung cancer

Lung adenocarcinoma may be cornered by a recent finding coming from a study published on Nov. 30, 2023, in the Proceedings of the National Academy of Sciences. This investigation has unveiled that a tumor suppressor molecule called RNA-binding motif protein 10 (RBM10) partners with two ribosomal proteins, which in turn inactivate the well-known oncogene Myc proto-oncogene protein (c-Myc). ....

Proceedings Of The National Academy Sciences , National Academy , Tulane University , Rna Binding Motif Protein 10 , C Myc , Lung Adenocarcinoma ,

CDR-Life Presents Precise Tumor and Patient Selection for CDR404: First-of-its-Kind Dual MAGE-A4 T-cell Engager, at ESMO Congress 2023

- CDR404 represents a potential paradigm shift in the development of T-cell engagers for solid cancers - Epithelial cancer indications eligible for CDR404 Phase 1 trial include non-small cell lung carcinoma (NSCLC), head & neck squamous cell carcinoma and bladder cancer ZÜRICH, Switzerland, Oct. 23, 2023 (GLOBE NEWSWIRE) CDR-Life Inc. presented findings on tumor target expression and precise patient selection for the upcoming Phase 1 trial of CDR404 (Abstract 200P), a first-of-its-kind bispec ....

United States , Emiliano Calvo , Swethajit Biswas , Globe Newswire Inc , Cancer Genome Atlas , Senior Investigator , Chief Medical Officer , Presentation Details , Precise Tumor , Patient Selection , Squamous Cell Carcinoma , Lung Adenocarcinoma , Bladder Cancer , Rna Expression , Solid Tumors , Bladder Cancers , Expression Levels , Patient Selection , Phase 1 Trial , Tumor Types ,

HDAC3 is critical in tumor development and therapeutic resistance in Kras-mutant non–small cell lung cancer

HDAC3 is critical in tumor development and therapeutic resistance in Kras-mutant non–small cell lung cancer
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Representative He Stained , Cancer Genome Atlas , Lung Adenocarcinoma ,