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Chapter 1: In the Path of the Pandemic

A novel coronavirus would come to affect every ward, clinician, researcher and patient at Massachusetts General Hospital. ....

United States , James Wilson , Ingat Lennes , Wenlong Dai , Jochen Lennerz , Dan Barouch , Bruce Walker , Ann Prestipino , Peter Dunn , Theresa Gallivan , Ed Raeke , Kyan Safavi , Orhun Muratoglu , Kathryn Hibbert , David Hooper , Robert Kacmarek , Paul Biddinger , Mason Freeman , Katrina Armstrong , Luk Vandenberghe , Erica Shenoy , Gene Therapy Program , Ragon Institute , Perioperative Services , Department Of Medicine , University Of Pennsylvania Perelman School Medicine ,

Synthetic viral vector and surgical approach enable efficient gene transfer into the inner ear of primates

A synthetic viral vector and a novel surgical approach developed at Mass Eye and Ear has enabled efficient gene transfer into the inner ear of nonhuman primates, a research team working towards the development of effective treatments for hearing loss and vestibular disorders has reported. ....

Luk Vandenberghe , Michael Mckenna , Konstantina Stankovic , Emily Henderson , Nature Communications , Bertarelli Foundation Professor , Department Of Otolaryngology , Harvard Medical School , Division Of Otology , Grousbeck Gene Therapy Center At Mass Eye , Mass Eye , Grousbeck Gene Therapy Center , Harvard Medical , Neck Surgery , Stanford University School , Chief Medical Officer , Viral Vector , Gene Therapy , Gene Transfer , Hearing Loss , Medical School ,

Surgically Delivered AAV Enables Gene Transfer in Monkeys' Inner Ear

An AAV vector efficiently transferred genetic cargo to the inner ear of nonhuman primates via a surgical procedure, which may translate to human therapies. ....

Luk Vandenberghe , Michael Mckenna , Konstantina Stankoovic , Nature Communications , Stanford University School Of Medicine , Harvard Medical School , Grousbeck Gene Therapy Center At Mass Eye , Grousbeck Gene Therapy Center , Mass Eye , Harvard Medical , Stanford University School ,

Synthetic viral vector and surgical technique effectively deliver genetic cargo to inner ear in preclinical study

Synthetic viral vector and surgical technique effectively deliver genetic cargo to inner ear in preclinical study
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United States , Luk Vandenberghe , Lukasd Landegger , Fotini Nicolaou , Brianm Lin , Rudolphj Beiler , Nicholasa Dewyer , Michelled Valero , Dorothea Buckler , Michael Mckenna , Williamf Sewell , Eva Andres Mateos , Julio Sanmiguel , Jean Phillips , Carmen Unzu , Konstantina Stankovic , Kathrini Bourdeu , Zwanziger Foundation , Bertarelli Foundation Professor , Nature Communications , Harvard Medical School , Barnes Foundation , Division Of Otology , Akouos Inc , Department Of Otolaryngology , Lonza Inc ,

Protection, Accessibility, Durability

Protection, Accessibility, Durability
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United States , Joan Miller , Luk Vandenberghe , David Glendenning Cogan , Elisa Schwartz , Nerea Zabaleta Lasarte , George Mason University Fast , Us Centers For Disease , National Institutes Of Health , Melinda Gates Foundation , Harvard Medical School , Grousbeck Gene Therapy Center , University Of Pennsylvania , Grousbeck Gene Therapy Center At Mass Eye , Massachusetts Consortium For Pathogen Readiness Mass , Massachusetts Eye , Cell Host , Mass Eye , David Glendenning Cogan Professor , Massachusetts General Hospital , Zabaleta Lasarte , Mass General , Novartis Gene Therapies , Massachusetts Consortium , Pathogen Readiness , George Mason University Fast Grants ,