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Acute rehabilitation following traumatic anterior shoulder dislocation (ARTISAN): pragmatic, multicentre, randomised controlled trial

Objective To assess the effects of an additional programme of physiotherapy in adults with a first-time traumatic shoulder dislocation compared with single session of advice, supporting materials, and option to self-refer to physiotherapy.

Design Pragmatic, multicentre, randomised controlled trial (ARTISAN).

Setting and participants Trauma research teams at 41 UK NHS Trust sites screened adults with a first time traumatic anterior shoulder dislocation confirmed radiologically, being managed non-operatively. People were excluded if they presented with both shoulders dislocated, had a neurovascular complication, or were considered for surgical management.

Interventions One session of advice, supporting materials, and option to self-refer to physiotherapy (n=240) was assessed against the same advice and supporting materials and an additional programme of physiotherapy (n=242). Analyses were on an intention-to-treat basis with secondary per protocol analyses.

Ma ....

East Suffolk , United Kingdom , North Yorkshire , West Suffolk , United Kingdom General , Glasgow City , City Of , West Midlands , Henry Nwankwo , Christopher Ratcliffe , Hannah Riley , Nicola Parker , Maria Mestre , Rachel Chester , Alison Armstrong , Rebeccas Kearney , Hannah Craig , Aileen Nacorda , Kathryn Allison , Fiona Carleton , Chandramohan Panneerselvam , Leanne Dymott , David Torgerson , David Bailey , Hayley Potter , Sarah Melling ,

Higher dose corticosteroids in patients admitted to hospital with COVID-19 who are hypoxic but not requiring ventilatory support (RECOVERY): a randomised, controlled, open-label, platform trial

In patients hospitalised for COVID-19 with clinical hypoxia who required either no
oxygen or simple oxygen only, higher dose corticosteroids significantly increased
the risk of death compared with usual care, which included low-dose corticosteroids.
The RECOVERY trial continues to assess the effects of higher dose corticosteroids
in patients hospitalised with COVID-19 who require non-invasive ventilation, invasive
mechanical ventilation, or extracorporeal membrane oxygenation. ....

United Kingdom , Northern Ireland , Raphl Hamers , Damodar Paudel , Peterw Horby , Marian Knight , Edmund Juszczak , Richard Haynes , Mark Campbell , Roshan Kumar Jha , Evelyne Kestelyn , Marion Mafham , David Demets , Thomas Jaki , Mayah Buch , Sauln Faust , Uun Sumardi , Jonathanr Emberson , Pham Ngoc Thach , John Amuasi , Manisha Rawal , Peter Sandercock , Jeremy Nel , Natalie Staplin , Robert Fowler , J Kenneth Baillie ,