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Dead from a fentanyl overdose. his mother, deena, found him in the basement. i can tell you miss him. i do, i do. i miss him every day, i have a hole in my heart. reporter: matthew, who strugemmed with depression, it taken a pill laced with fentanyl 100 times more potent than heroin. i saw matthew and quickly turned him over and i knew he was gone. reporter: nearly 75% of the drug-related deaths last year were attributed to illegal fentanyl. it s smuggled into the u.s., mainly from mexico, hidden in tires, trucks, even loads of frozen fish. in lor aido, texas, seizures at the border are up 1,500% this year. we re seeing them in very small packages, which makes it even more challenging for our workforce to interdict. reporter: the cartels lace drugs like cocaine and heroin with fentanyl, and use it to make fake pain pills that end up on american streets. the u.s. government seized 1.8 ....