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The pair are targeting approval by the end of the year GlaxoSmithKline PLC (LON:GSK) announced that the COVID-19 vaccine developed with French giant Sanofi SA demonstrated strong immune responses in mid-stage trials. The jab showed 95% to 100% seroconversion following a second injection in all age groups, with acceptable tolerability and with no safety concerns. It prompted strong neutralising antibody levels that were comparable to those generated by natural infection, with higher levels observed in adults up to 59 years old. Participants who previously contracted the virus experienced high antibody levels with the first dose, which the pharma company said suggests strong potential for development as a booster vaccine. ....
17 May 2021 | 07:30am StockMarketWire.com - Pharma giants GlaxoSmtihKline and Sanofi said they would move to a phase 3 trial of their Covid-19 vaccine in the coming weeks after a phase 2 trial showed strong rates of immune responses in all adult age groups. The phase 2 study interim results show that the adjuvanted recombinant vaccine candidate triggered a strong immune response amongst adults of all age groups with 95% to 100% seroconversion rates and neutralizing antibodies that were comparable to those generated by natural infection, GSK said. The phase 3 trial is expected to enrol more than 35,000 adult participants from a broad range of countries and will assess the efficacy of two vaccine formulations including the D614 (Wuhan) and B.1.351 (South African) variants, it added. ....
17 May 2021 | 12:01pm StockMarketWire.com - Weakness in the mining and banking sectors and strength in sterling as the UK took the next step in its reopening helped put the FTSE 100 under pressure on Monday. By midday the index was down 0.7% at 6,994.01. Technical products and services provider Diploma rallied 7.3% to £29.50, having upgraded its annual outlook thanks to a boost from acquisitions, particularly WCW, and improved underlying trading. Diploma s annual revenue was now expected to be slightly better than 40% ahead of the 2020 financial year, with an increase in its margin towards 19%. Low-cost carrier Ryanair rose 0.6% even as it swung to a €815 million full-year loss after the pandemic hammered global travel markets. ....