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Monitoring the potency of cell therapies using bioelectronic assays


Monitoring the potency of cell therapies using bioelectronic assays
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Chimeric antigen receptor (CAR) T and natural killer (NK) therapies may become the future of cancer treatment. Dr Jim Ross explains how bioelectronic assays are a non-invasive, label-free approach built for real-time, dynamic assessment of cell therapy potency.
Personalised medicine is now within reach for thousands of cancer patients thanks to immunotherapies such as CAR T cells. This cell therapy involves training a patient’s immune system through genetic engineering to recognise tumour cells as foreign bodies and attack them directly, without attacking healthy tissue. In 2017, the US Food and Drug Administration (FDA) approved Kymriah, the first CAR T-cell therapy, for the treatment of B-cell acute lymphoblastic leukaemia. Now, patients across the US can access the treatment at any one of over 130 treatment centers. ....

United States , Jim Ross , Axion Biosystems , Lohitash Karumbaiah , Novartis Pharmaceuticals Corporation , Drug Administration , Cancer Research Institute , Associate Professor , Regenerative Medicine Lohitash Karumbaiah , Chief Technology Officer , ஒன்றுபட்டது மாநிலங்களில் , ஜிம் ரோஸ் , அச்சு உயிர் அமைப்புகள் , நோவர்த்திச் மருந்துகள் நிறுவனம் , புற்றுநோய் ஆராய்ச்சி நிறுவனம் , இணை ப்ரொஃபெஸர் , தலைமை தொழில்நுட்பம் அதிகாரி ,

'Brain glue' may aid in functional neural repair after severe TBI


Brain glue may aid in functional neural repair after severe TBI
At a cost of $38 billion a year, an estimated 5.3 million people are living with a permanent disability related to traumatic brain injury in the United States today, according to the Centers for Disease Control and Prevention. The physical, mental and financial toll of a TBI can be enormous, but new research from the University of Georgia provides promise.
In a new study, researchers at UGA s Regenerative Biosciences Center have demonstrated the long-term benefits of a hydrogel, which they call brain glue, for the treatment of traumatic brain injury. The new study provides evidence that not only does the gel protect against loss of brain tissue after a severe injury, but it also might aid in functional neural repair. ....

United States , Parastoo Azadi , Rameen Forghani , Charles Latchoumane , Lohitash Karumbaiah , Emily Henderson , Centers For Disease , Environmental Sciences , Carbohydrate Research Center , Sciences Advances , University Of Georgia , University Of Georgia College Agricultural , National Science Materials Innovation Platform , Duke University , Regenerative Biosciences Center , Disease Control , Biosciences Center , ஒன்றுபட்டது மாநிலங்களில் , எமிலி ஹென்டர்சன் , மையங்கள் க்கு நோய் , சுற்றுச்சூழல் அறிவியல் , கார்போஹைட்ரேட் ஆராய்ச்சி மையம் , பல்கலைக்கழகம் ஆஃப் ஜார்ஜியா , தேசிய அறிவியல் பொருட்கள் கண்டுபிடிப்பு நடைமேடை , டியூக் பல்கலைக்கழகம் , மீளுருவாக்கம் உயிர் அறிவியல் மையம் ,