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Brain organoids provide a valuable model to study autism

Variations in the 16p11.2 region of the genome are associated with autism spectrum disorder. While people with genetic deletions in this region have larger heads (macrocephaly) and people with genetic duplications have smaller heads (microcephaly), both variation types affect brain development and function. ....

San Diego , United States , University Of California San Diego , Lilia Iakoucheva , Alysson Muotri , Emily Henderson , Uc San Diego Stem Cell Program , Sanford Consortium For Regenerative Medicine , Uc San Diego School Of Medicine , California San Diego School , Molecular Psychiatry , Diego School , Diego Stem Cell Program , Sanford Consortium , Blood Vessels , Stem Cells ,

Brain Organoids Mimic Head Size Changes Associated with Type of Autism

Brain Organoids Mimic Head Size Changes Associated with Type of Autism
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San Diego , United States , University Of California San Diego , Lilia Iakoucheva , Jorge Urresti , Jonathan Sebat , Kevin Chau , Clebera Trujillo , Akula Bala Pramod , Megha Amar , Pan Zhang , Johnr Yates , Patricia Moran Losada , Sarah Romero , Priscillad Negraes , Jolene Diedrich , Danny Antaki , Nam Kyung Yu , Alysson Muotri , Scripps Research , Uc San Diego Stem Cell Program , Sanford Consortium For Regenerative Medicine , National Institutes Of Health , Simons Foundation For Autism Research , Uc San Diego School Of Medicine , California San Diego School ,