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PROs for Cutaneous Chronic GVHD After Transplant Tied to Disease Severity, Mortality

Baseline QOL, symptom burden could inform risk stratification, treatment decisions ....

University Of Pennsylvania , United States , Sandra Mitchell , Edward Cowen , Charles Bankhead , Emily Baumrin , National Cancer Institute In Rockville , Population Sciences , Division Of Cancer , Cancer Control , National Cancer Institute , Dermatology Branch , National Institute , Skin Diseases , Functional Assessment , Cancer Therapy Bone Marrow Transplantation , Lee Symptom Scale , Medpage Today ,

Axatilimab Gets Priority Review for Chronic Graft-vs-Host Disease

The application is supported by data from the phase 2 AGAVE-201 study. ....

Drug Administration , Priority Review , Biologics License Application , Lee Symptom Scale , Prescription Drug User Fee Act ,

Form 424B5 Syndax Pharmaceuticals

Form 424B5 Syndax Pharmaceuticals
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Axatilimab Elicits Responses With Manageable Safety in Recurrent/Refractory cGVHD

Axatilimab induced rapid and durable responses with an acceptable toxicity profile at all doses analyzed with highest efficacy observed at the 0.3-mg/kg dose in patients with recurrent or refractory chronic graft-vs-host disease. ....

United States , Daniel Wolff , National Institutes Of Health , University Hospital Of Regensburg , University Hospital , Plenary Session , National Institutes , North America , Middle East , Lee Symptom Scale ,

Incyte and Syndax Present Additional Data from Positive AGAVE-201 Trial at ASH Plenary Session Showing Axatilimab Efficacy Including Durable Responses in Chronic Graft-Versus-Host Disease

WILMINGTON, Del. & WALTHAM, Mass. (BUSINESS WIRE) Dec 10, 2023 ....

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