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Gut Flora Produces Red Meat Byproduct That Increases Heart Disease Risk

A diet rich in red meat correlates with increased risk for cardiovascular disease but the underlying genetic and biochemical mechanisms for this link have not been clear until now. A new study from researchers at the Cleveland Clinic identifies the genetic machinery and biochemical process through which gut bacteria sequentially convert carnitine present in a red-meat rich diet into a metabolite called TMAO that promotes blood clotting and atherosclerosis. ....

Stanley Hazen , Microbiome Human Health , Cardiovascular Disease Metabolic Sciences , Leducq Foundation , Procter Gamble , Lung Blood Institute , National Heart , Human Health , Cardiovascular Disease , Metabolic Sciences , Cleveland Clinic , Nature Microbiology , Blood Institute ,