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Biopharming can help pioneer new treatments but cumbersome, outdated regulations block innovation

Obtaining medicines from plants is not new. Aspirin was first isolated from the bark of the willow tree in the 18th century, and many other common pharmaceuticals have been purified from the world’s flora. These medicines include morphine, codeine, digitalis, the laxative Metamucil, and the anti‐​cancer drugs paclitaxel and vinblastine. A notable plant‐​derived product that has emerged from traditional Chinese medicine is artemisinin, an important treatment for malaria.Spurred by the COVID-19 pandemic, many laboratories are reorienting their research to not only look at promising compounds that occur naturally in plants, but also to manipulate plants to produce high‐​value pharmaceuticals, a practice called “biopharming.” Academics and biotech companies are using molecular genetic engineering techniques to reprogram plants including corn, potatoes, rice, and bananas, among others to produce significant concentrations of pharmaceuticals, including vaccines. Unfortunat ....

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