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Best allocation protocol for limited cholera vaccines

Limited cholera vaccines and negligible one-dose vaccine efficacies for children under 5 complicates vaccination strategies during cholera outbreaks. ....

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There's no crystal ball for modeling the pandemic


There’s no crystal ball for modeling the pandemic
Mathematical modelers explain challenges, limitations of their work to predict COVID-19 outcomes
February 22, 2021

By Sabrina Richards
/ Fred Hutch News Service
While models can point to key variables that could slow the spread of SARS-CoV-2, modelers caution against expecting them to predict the exact numbers of cases of COVID-19.
Getty Images Illustration
Dr. Laura Matrajt didn’t expect to make much noise on Twitter. She just wanted to clarify a term she’d seen sowing confusion on social media.
It was mid-March 2020, and the term was “flattening the curve.”
“I was seeing people in my social media discussing, ‘Is it useful? Is it not useful?’” she said. “Some were saying, ‘People are exaggerating, [SARS-CoV-2] is just like the flu.’” ....

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Tip Sheet: Diversity in vaccine clinical trials, behind-the-scenes look at COVID-19 biostats, new cell therapy approved, plus meet 'Megasphaera hutchinsoni'

Tip Sheet: Diversity in vaccine clinical trials, behind-the-scenes look at COVID-19 biostats, new cell therapy approved, plus meet 'Megasphaera hutchinsoni'
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Math Problem: What's The Best Strategy For COVID-19 Vaccination?


Originally published on January 11, 2021 3:36 pm
Only a vaccine will save America from the COVID -19 pandemic. At least that s the opinion of nearly all public health officials.
Obviously, vaccine manufacturers are critical to any vaccine campaign. But there s another group that plays a less obvious but still crucial role in making sure vaccines do what they re intended: mathematicians.
Even if the Biden administration releases all available doses of the two authorized COVID-19 vaccines, for a while at least, supplies will remain limited. How best to use that limited supply is a question mathematicians can help answer.
Mathematical models are very, very useful to guide policy, says Laura Matrajt, a builder of mathematical models at the Fred Hutchinson Cancer Research Center in Seattle. They can help with decisions about who gets the vaccine first when supplies are limited. ....

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