Mazyar Shadman, MD, MPH, details the efficacy of BTK inhibitors in the frontline treatment of CLL as well as safety considerations in the relapsed/refractory setting.
Death and Injury Victims in Subang Bus Accident Reach 64 People kompas.id - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from kompas.id Daily Mail and Mail on Sunday newspapers.
Shock-breakout emission is light that arises when a shockwave, generated by the core-collapse explosion of a massive star, passes through its outer envelope. Hitherto, the earliest detection of such a signal was at several hours after the explosion1, although a few others had been reported2–7. The temporal evolution of early light curves should provide insights into the shock propagation, including explosion asymmetry and environment in the vicinity, but this has been hampered by the lack of multiwavelength observations. Here we report the instant multiband observations of a type II supernova (SN 2023ixf) in the galaxy M101 (at a distance of 6.85 ± 0.15 Mpc; ref. 8), beginning at about 1.4 h after the explosion. The exploding star was a red supergiant with a radius of about 440 solar radii. The light curves evolved rapidly, on timescales of 1−2 h, and appeared unusually fainter and redder than predicted by the models9–11 within
AAM Training auditedmedia.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from auditedmedia.com Daily Mail and Mail on Sunday newspapers.
Experts discuss considerations around first-line treatment selection for HER2-positive metastatic breast cancer, including when to diverge from the standard-of-care treatment, as well as the role of brain MRIs at diagnosis.